Results 101 to 110 of about 2,773,990 (319)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Evolution and comparative haemoglobin oxygen binding in new zealand mudfishes [PDF]
, 2007 New Zealand's five endemic mudfish (Neochanna spp.) species have distributions that differ both geographically and by habitat type. Differences in habitat preferences between species have led to the proposal of an evolutionary series within the group.
Brijs, Jeroen
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Modelling the distribution of the oxygen-haemoglobin dissociation curve in vivo: An observational study [PDF]
Few studies have explored the variability of the oxygen-haemoglobin dissociation curve in vivo.96,428 blood gas measurements were obtained (80,376 arterial, 6959 venous) from a cohort of 7656 patients who were admitted to a large UK teaching hospital ...
Cruickshank, Simon +10 more
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OxygenUterine fibroids (leiomyomas) are common benign smooth muscle tumors that impose substantial symptom burden and healthcare costs worldwide. Although uterine fibroid (leiomyoma) pathogenesis is multifactorial, hypoxia has emerged as a key feature of the ...
Sruthi Tatavarthi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Targeting Catechol Oxidation via Boron Complexation: From Chemistry to Biology
OxygenCatechol (benzene-1,2-diol) is a highly versatile chemical motif that plays a central role in both terrestrial and marine systems, where its reactivity is governed by a combination of enzymatic oxidation and non-enzymatic interactions.
Valery M. Dembitsky +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
OxygenChlorine dioxide (ClO2) is a neutral oxidant molecule with a short lifespan once in contact with electron donors (organic matter). ClO2 solutions have antiviral, antibacterial, antifungal, anti-protozoan, anti-inflammatory, anticancer, and wound-healing ...
Enrique A. Martinez Mosqueira +3 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
, 2010 Today, the Brant Family continues to be involved in the communities in which it serves. Integrity and ethics have always guided Indiana Oxygen’s way of conducting business.
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