Results 121 to 130 of about 4,498,384 (306)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Hypoxia in Uterine Fibroids: Role in Pathobiology and Therapeutic Opportunities
OxygenUterine fibroids are the most common tumors in females, affecting up to 70% of women worldwide, yet targeted therapeutic options are limited. Oxidative stress has recently surfaced as a key driver of fibroid pathogenesis and provides insights into ...
Sydney L. Olson +4 more
doaj +1 more source
Oxygen diffusion barrier coating [PDF]
, 1987 A method for coating a titanium panel or foil with aluminum and amorphous silicon to provide an oxygen barrier abrogating oxidation of the substrate metal is developed.
Clark, Ronald K., Unnam, Jalaiah
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
OxygenA member of the Verbenaceae family, Aloysia citrodora, or lemon verbena, is a medicinal herb with antioxidant compounds. The aim of this study was to develop a green, optimized method for the bioactive compound (carotenoids, ascorbic acid, and ...
Vassilis Athanasiadis +5 more
doaj +1 more source
Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
Diffusion and Spectroscopy of H2 in Myoglobin
OxygenThe diffusional dynamics and vibrational spectroscopy of molecular hydrogen (H2) in myoglobin (Mb) is characterized. Hydrogen has been implicated in a number of physiologically relevant processes, including cellular aging or inflammation.
Jiri Käser, Kai Töpfer, Markus Meuwly
doaj +1 more source
Dissolved Oxygen Monitoring in Kings River and Leatherwood Creek [PDF]
, 2016 The Clean Water Act (CWA) establishes the basic structure used to regulate water quality. Under the CWA, States are required to assess water bodies relative to water‐quality standards and designated beneficial uses and then to ...
Cummings, Eric +3 more
core +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
BioMedical Engineering OnLineBackground Critically ill patients undergoing liberation often encounter various physiological and clinical complexities and challenges. However, whether the combination of hyperbaric oxygen and in-cabin ventilator therapy could offer a comprehensive ...
Yinliang Qi +3 more
doaj +1 more source