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Oxylipins in moss development and defense [PDF]
Oxylipins are oxygenated fatty acids that participate in plant development and defense against pathogen infection, insects and wounding. Initial oxygenation of substrate fatty acids is mainly catalyzed by lipoxygenases and alpha-dioxygenases but can also
Inés ePonce De León +2 more
doaj +7 more sources
Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population
BackgroundOxylipins are inflammatory biomarkers derived from omega-3 and-6 fatty acids implicated in inflammatory diseases but have not been studied in a genome-wide association study (GWAS).
Teresa Buckner +17 more
doaj +5 more sources
Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation
Oxylipins are lipid mediators generated during infection for regulating inflammatory responses, but how they are removed is not completely clear. Here the authors show that cellular oxylipin removal is linked to mitochondria β-oxidation by CPT1, a ...
Konstantinos Kotzamanis +2 more
exaly +2 more sources
Effects of a 12-week high-α-linolenic acid intervention on EPA and DHA concentrations in red blood cells and plasma oxylipin pattern in subjects with a low EPA and DHA status [PDF]
The essential omega-3 fatty acid alpha-linolenic acid (ALA, 18:3n3) can be converted into EPA and DHA. The aim of the present study was to determine the effect of a high-ALA diet on EPA and DHA levels in red blood cells (RBCs) and their oxylipins in the ...
Theresa Greupner +2 more
exaly +5 more sources
Summary: Oxylipins are major immunomodulating mediators, yet studies of inflammation focus mainly on cytokines. Here, using a standardized whole-blood stimulation system, we characterized the oxylipin-driven inflammatory responses to various stimuli and ...
Etienne Villain +58 more
doaj +1 more source
Immune function changes across the life stages; for example, senior adults exhibit a tendency towards a weaker cell-mediated immune response and a stronger inflammatory response than younger adults.
Johanna von Gerichten +9 more
doaj +1 more source
Plant oxylipins are signaling molecules produced from fatty acids by oxidative pathways, mainly initiated by 9- and 13-lipoxygenases (9-LOX and 13-LOX), alpha-dioxygenases or non-enzymatic oxidation.
Yovanny Izquierdo +10 more
doaj +1 more source
Specificity of lipoxygenase pathways supports species delineation in the marine diatom genus Pseudo-nitzschia. [PDF]
Oxylipins are low-molecular weight secondary metabolites derived from the incorporation of oxygen into the carbon chains of polyunsaturated fatty acids (PUFAs). Oxylipins are produced in many prokaryotic and eukaryotic lineages where they are involved in
Nadia Lamari +5 more
doaj +1 more source
Coronary artery disease (CAD) is among the leading causes of death globally. The American Heart Association recommends that people should consume more PUFA-rich plant foods to replace SFA-rich ones to lower serum cholesterol and prevent CAD.
Kuang-Mao Chiang +6 more
doaj +1 more source
Menadione-induced oxidative stress re-shapes the oxylipin profile of Aspergillus flavus and its lifestyle [PDF]
Aspergillus flavus is an efficient producer of mycotoxins, particularly aflatoxin B1, probably the most hepatocarcinogenic naturally-occurring compound.
Cigliano, Riccardo Aiese +9 more
core +5 more sources

