Oxylipins in moss development and defense [PDF]
Frontiers in Plant Science, 2015 Oxylipins are oxygenated fatty acids that participate in plant development and defense against pathogen infection, insects and wounding. Initial oxygenation of substrate fatty acids is mainly catalyzed by lipoxygenases and alpha-dioxygenases but can also
Inés ePonce De León +2 more
doaj +7 more sources
Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population
Frontiers in Nutrition, 2023 BackgroundOxylipins are inflammatory biomarkers derived from omega-3 and-6 fatty acids implicated in inflammatory diseases but have not been studied in a genome-wide association study (GWAS).
Teresa Buckner +17 more
doaj +5 more sources
Comprehensive Analysis of Different Subtypes of Oxylipins to Determine a LC–MS/MS Approach in Clinical Research [PDF]
MetabolitesBackground/Objectives: Different oxylipin subtypes have unique biological properties, requiring effective analytical protocols. However, establishing a complete pathway detection protocol for comprehensive oxylipin analysis is challenging.
Yurou Zhao +7 more
doaj +2 more sources
Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation
Nature Communications, 2022 Oxylipins are lipid mediators generated during infection for regulating inflammatory responses, but how they are removed is not completely clear. Here the authors show that cellular oxylipin removal is linked to mitochondria β-oxidation by CPT1, a ...
Konstantinos Kotzamanis +2 more
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The Patatin-Containing Phospholipase A pPLAIIα Modulates Oxylipin Formation and Water Loss in Arabidopsis thaliana [PDF]
Molecular Plant, 2012 The patatin-related phospholipase A (pPLA) hydrolyzes membrane glycerolipids to produce monoacyl compounds and free fatty acids. Phospholipids are cleaved by pPLAIIα at the sn-1 and sn-2 positions, and galactolipids, including those containing ...
Yong Zheng, Hieu Sy Vu, Ruth Welti
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Oxylipin Profiling of Alzheimer’s Disease in Nondiabetic and Type 2 Diabetic Elderly
Metabolites, 2019 Oxygenated lipids, called “oxylipins,” serve a variety of important signaling roles within the cell. Oxylipins have been linked to inflammation and vascular function, and blood patterns have been shown to differ in type 2 diabetes (T2D ...
Jill K Morris +2 more
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Esterified Oxylipins: Do They Matter?
Metabolites, 2022 Oxylipins are oxygenated metabolites of fatty acids that share several similar biochemical characteristics and functions to fatty acids including transport and trafficking.
Carmen E. Annevelink +2 more
doaj +3 more sources
Workflow for the Isolation and Characterisation of Human Milk Extracellular Vesicles (HMEVs) and Their Inflammatory Biomarker Profile [PDF]
Journal of Extracellular BiologyHuman milk extracellular vesicles (HMEVs), secreted by mammary epithelial cells, are enriched in bioactive molecules that support intestinal epithelial integrity.
Jose Luis Moreno‐Casillas +12 more
doaj +2 more sources
The polyunsaturated fatty acid and oxylipin plasma signature of aneurysmal subarachnoid haemorrhage, case-control study [PDF]
NeurotherapeuticsDelayed cerebral ischemia (DCI) following aneurysmal subarachnoid haemorrhage (aSAH) is a complex and acute condition with limited options for early detection and effective treatments.
M.A. Franssen +11 more
doaj +2 more sources
Thermal Stress-Induced Alterations to Oxylipin Signal Receptors in the Cnidarian-Dinoflagellate Symbiosis. [PDF]
Environ MicrobiolThermal stress significantly alters signalling receptor abundance in the model cnidarian Exaiptasia diaphana. TRPA1, EP2 and GRIK2 increased under elevated temperatures, while EP4 remained unchanged, indicating differential thermal modulation of oxylipin‐ and glutamate‐linked pathways.
Gamba AG +6 more
europepmc +2 more sources