Results 11 to 20 of about 9,312 (214)

Comprehensive Analysis of Different Subtypes of Oxylipins to Determine a LC–MS/MS Approach in Clinical Research [PDF]

Metabolites
Background/Objectives: Different oxylipin subtypes have unique biological properties, requiring effective analytical protocols. However, establishing a complete pathway detection protocol for comprehensive oxylipin analysis is challenging.
Yurou Zhao, Zhengyu Fang, Zeyu Li, Yizhe Liu, Yang Bai, Xiaoqing Wang, Hongjun Yang, Na Guo   +7 more
doaj   +2 more sources

Esterified Oxylipins: Do They Matter?

Metabolites, 2022
Oxylipins are oxygenated metabolites of fatty acids that share several similar biochemical characteristics and functions to fatty acids including transport and trafficking.
Carmen E. Annevelink, Rachel E. Walker, Gregory C. Shearer   +2 more
doaj   +3 more sources

The prognostic and therapeutic significance of polyunsaturated fatty acid‐derived oxylipins in ST‐segment elevation myocardial infarction [PDF]

iMeta
Polyunsaturated fatty acid‐derived oxylipins regulate systemic inflammation and exert cardiovascular effects, yet their role in ST‐segment elevation myocardial infarction (STEMI) remains unclear. Herein, we used targeted metabolomics and machine learning
Zhiyong Du, Yingyuan Lu, Ying Ma, Yunxiao Yang, Wei Luo, Sheng Liu, Ming Zhang, Yong Wang, Lei Li, Chun Li, Wei Wang, Hai Gao   +11 more
doaj   +2 more sources

Workflow for the Isolation and Characterisation of Human Milk Extracellular Vesicles (HMEVs) and Their Inflammatory Biomarker Profile [PDF]

Journal of Extracellular Biology
Human milk extracellular vesicles (HMEVs), secreted by mammary epithelial cells, are enriched in bioactive molecules that support intestinal epithelial integrity.
Jose Luis Moreno‐Casillas, Laura Ripoll‐Seguer, Isabel Ten‐Doménech, Marta Gómez‐Ferrer, Pilar Sepúlveda, Abel Albiach‐Delgado, Juan Daniel Sanjuan‐Herráez, María Gormaz, David Pérez‐Guaita, Bernhard Lendl, María Cernada, Guillermo Quintás, Julia Kuligowski   +12 more
doaj   +2 more sources

Mutations in Components of the TREX‐2 Complex Result in Misexpression of the Kelch‐Domain F‐Box Protein KFB39 Promoter in Arabidopsis thaliana [PDF]

Plant Direct, Volume 10, Issue 2, February 2026.
ABSTRACT Arabidopsis thaliana gene At2g44130 encodes a Kelch‐like domain F‐box protein designated KFB39 and was previously shown to be specifically expressed on exposure to the oxylipin cis‐jasmone. In order to better understand the regulation of At2g44130, a forward genetic screen was carried out to identify mutants in which a promoter‐GUS fusion was ...
Michaela C. Matthes, Smita Kurup, John A. Pickett, Johnathan A. Napier   +3 more
wiley   +2 more sources

Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP‐43 Mouse Model of Frontotemporal Dementia [PDF]

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
TDP‐43 overexpressing mice, a genetic model of frontotemporal dementia, exhibit dramatic changes in their small intestinal endocannabinoidome members, in terms of both altered concentrations of lipid mediators and expression of some of their receptors (Cnr1, Gpr119, Gpr55, Pparg) and metabolic enzymes (Napepld, Faah). Also, the levels of some oxylipins
Hayatte‐Dounia Mir, Giada Giorgini, Irene Santos‐García, Elizabeth Dumais, Carmen Rodríguez‐Cueto, Eva de Lago, Cristoforo Silvestri, Nicolas Flamand, Javier Fernández‐Ruiz, Vincenzo Di Marzo   +9 more
wiley   +2 more sources

The polyunsaturated fatty acid and oxylipin plasma signature of aneurysmal subarachnoid haemorrhage, case-control study [PDF]

Neurotherapeutics
Delayed cerebral ischemia (DCI) following aneurysmal subarachnoid haemorrhage (aSAH) is a complex and acute condition with limited options for early detection and effective treatments.
M.A. Franssen, M.A. Tjerkstra, M. Heijink, S.A. Rotman, D. Verbaan, E. van Bavel, W.P. Vandertop, H.E. de Vries, J.M. Coutinho, M.A. Giera, I.A. Mulder, G. Kooij   +11 more
doaj   +2 more sources

Understanding the role of oxylipins in Cannabis to enhance cannabinoid production [PDF]

Frontiers in Plant Science
Phytocannabinoids are medically important specialized defense compounds that are sparsely distributed among plants, yet Cannabis sativa can synthesize unprecedented amounts of these compounds within highly specialized surface cell factories known as ...
Gayathree I. Senevirathne, Gayathree I. Senevirathne, Anthony R. Gendall, Anthony R. Gendall, Anthony R. Gendall, Anthony R. Gendall, Kim L. Johnson, Kim L. Johnson, Kim L. Johnson, Matthew T. Welling, Matthew T. Welling, Matthew T. Welling   +11 more
doaj   +2 more sources

Axial and radial oxylipin transport [PDF]

Plant Physiology, 2015
Jasmonates are oxygenated lipids (oxylipins) that control defense gene expression in response to cell damage in plants. How mobile are these potent mediators within tissues? Exploiting a series of 13-lipoxygenase (13-lox) mutants in Arabidopsis (Arabidopsis thaliana) that displays impaired jasmonic acid (JA) synthesis in specific cell types and using ...
Gasperini, Debora, Chauvin, Adeline, Acosta, Ivan F., Kurenda, Andrzej, Stolz, Stéphanie, Chételat, Aurore, Wolfender, Jean-Luc, Farmer, Edward E   +7 more
openaire   +4 more sources

Oxylipins in fungi [PDF]

The FEBS Journal, 2011
In nearly every living organism, metabolites derived from lipid peroxidation, the so‐called oxylipins, are involved in regulating developmental processes as well as environmental responses. Among these bioactive lipids, the mammalian and plant oxylipins are the best characterized, and much information about their physiological role and biosynthetic ...
Florian, Brodhun, Ivo, Feussner
openaire   +2 more sources