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iScience, 2023 Summary: Oxylipins are major immunomodulating mediators, yet studies of inflammation focus mainly on cytokines. Here, using a standardized whole-blood stimulation system, we characterized the oxylipin-driven inflammatory responses to various stimuli and ...
Etienne Villain +58 more
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Frontiers in Immunology, 2023 Immune function changes across the life stages; for example, senior adults exhibit a tendency towards a weaker cell-mediated immune response and a stronger inflammatory response than younger adults.
Johanna von Gerichten +9 more
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Axial and radial oxylipin transport [PDF]
Plant Physiology, 2015 Jasmonates are oxygenated lipids (oxylipins) that control defense gene expression in response to cell damage in plants. How mobile are these potent mediators within tissues? Exploiting a series of 13-lipoxygenase (13-lox) mutants in Arabidopsis (Arabidopsis thaliana) that displays impaired jasmonic acid (JA) synthesis in specific cell types and using ...
Gasperini, Debora +7 more
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The FEBS Journal, 2011 In nearly every living organism, metabolites derived from lipid peroxidation, the so‐called oxylipins, are involved in regulating developmental processes as well as environmental responses. Among these bioactive lipids, the mammalian and plant oxylipins are the best characterized, and much information about their physiological role and biosynthetic ...
Florian, Brodhun, Ivo, Feussner
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Frontiers in Plant Science, 2021 Plant oxylipins are signaling molecules produced from fatty acids by oxidative pathways, mainly initiated by 9- and 13-lipoxygenases (9-LOX and 13-LOX), alpha-dioxygenases or non-enzymatic oxidation.
Yovanny Izquierdo +10 more
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Specificity of lipoxygenase pathways supports species delineation in the marine diatom genus Pseudo-nitzschia. [PDF]
PLoS ONE, 2013 Oxylipins are low-molecular weight secondary metabolites derived from the incorporation of oxygen into the carbon chains of polyunsaturated fatty acids (PUFAs). Oxylipins are produced in many prokaryotic and eukaryotic lineages where they are involved in
Nadia Lamari +5 more
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Metabolites, 2022 Coronary artery disease (CAD) is among the leading causes of death globally. The American Heart Association recommends that people should consume more PUFA-rich plant foods to replace SFA-rich ones to lower serum cholesterol and prevent CAD.
Kuang-Mao Chiang +6 more
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The Role of Chloroplast Membrane Lipid Metabolism in Plant Environmental Responses
Cells, 2021 Plants are nonmotile life forms that are constantly exposed to changing environmental conditions during the course of their life cycle. Fluctuations in environmental conditions can be drastic during both day–night and seasonal cycles, as well as in the ...
Ron Cook +2 more
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Menadione-induced oxidative stress re-shapes the oxylipin profile of Aspergillus flavus and its lifestyle [PDF]
, 2015 Aspergillus flavus is an efficient producer of mycotoxins, particularly aflatoxin B1, probably the most hepatocarcinogenic naturally-occurring compound.
Cigliano, Riccardo Aiese +9 more
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Frontiers in Immunology, 2023 IntroductionPhagocytosis of inhaled crystalline silica (cSiO2) particles by tissue-resident alveolar macrophages (AMs) initiates generation of proinflammatory eicosanoids derived from the ω-6 polyunsaturated fatty acid (PUFA) arachidonic acid (ARA) that ...
Olivia K. Favor +13 more
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