Journal of Chemistry, 2020 Herein, we described the modification of chitosan with cyanuric chloride as a mediator for preparation of chitosan-s-triazinyl-bis(2-aminomethylpyridine) and chitosan-s-triazinyl-bis(8-oxyquinoline) derivatives to be used as reagents for preparation of ...
Hessa H. Al-Rasheed +5 more
doaj +2 more sources
Liver microphysiological platforms for drug metabolism applications
Cell Proliferation, Volume 54, Issue 9, September 2021., 2021 Liver‐on‐a‐chip (LOC) devices are microfluidic platforms seeded with human liver cells able to recapitulate the functions, microphysiology, and drug metabolism that takes place in the human liver. Liver‐on‐a‐chip platforms in stand‐alone format and coupled to other microphysiological devices (multi‐organ platforms) can open doors towards accelerating ...
Gulsim Kulsharova, Akbota Kurmangaliyeva
wiley +1 more source
Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model
Antioxidants, 2020 A novel potent analog of the branched tail oxyquinoline group of hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors, neuradapt, has been studied in two treatment regimes in an in vitro hypoxia model on murine primary hippocampal cultures ...
Maria Savyuk +12 more
doaj +1 more source
Integrating Multiple Analytical Datasets to Compare Metabolite Profiles of Mouse Colonic-Cecal Contents and Feces. [PDF]
, 2015 The pattern of metabolites produced by the gut microbiome comprises a phenotype indicative of the means by which that microbiome affects the gut. We characterized that phenotype in mice by conducting metabolomic analyses of the colonic-cecal contents ...
Combs, Gerald F +5 more
core +2 more sources
Neurobiology of Disease, 2020 Identifying disease-causing pathways and drugs that target them in Parkinson's disease (PD) has remained challenging. We uncovered a PD-relevant pathway in which the stress-regulated heterodimeric transcription complex CHOP/ATF4 induces the neuron ...
Pascaline Aimé +6 more
doaj +1 more source
Supramolecular study, Hirshfeld analysis and theoretical study of 6-methoxyquinoline N-oxide dihydrate [PDF]
, 2013 In the crystal structure of 6-methoxyquinoline N-oxide dihydrate, C10H9NO2 center dot 2H(2)O, (I), the presence of two-dimensional water networks is analysed.
Hernandez, Geraldine +3 more
core +1 more source
The Integration of Positron Emission Tomography With Magnetic Resonance Imaging [PDF]
, 2008 A number of laboratories and companies are currently exploring the development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET).
Cherry, Simon R. +2 more
core +1 more source
Predictors of outcomes in diabetic foot osteomyelitis treated initially with conservative (nonsurgical) medical management: A retrospective study [PDF]
, 2016 The optimal way to manage diabetic foot osteomyelitis remains uncertain, with debate in the literature as to whether it should be managed conservatively (ie, nonsurgically) or surgically. We aimed to identify clinical variables that influence outcomes of
Catherine Gooday +5 more
core +1 more source
Carduus acicularis Bertol. (Asteraceae) en la Península Ibérica [PDF]
, 2009 El género Carduus L. (Cardueae, Asteraceae), tal y como se considera hoy día, comprende unas 90 especies eurasiáticas (Susanna & García-Jacas, 2007), con especial representación en la Región Mediterránea (Kazmi, 1964).
Arnelas, Itziar +2 more
core +3 more sources
[PdCl2{8-(di-tert-butylphosphinooxy)quinoline)}]: a highly efficient catalyst for Suzuki-Miyaura reaction [PDF]
, 2009 The complex [PdCl2(P-N)] containing the basic and sterically demanding 8-(di-tert-butylphosphinooxy)quinoline ligand (P-N) is a highly efficient catalyst for the coupling of phenylboronic acid with aryl bromides or aryl chlorides.
Antonaroli, S +4 more
core +2 more sources