Results 21 to 30 of about 1,461 (167)

Inhibitor of Differentiation‐3 and Estrogenic Endocrine Disruptors: Implications for Susceptibility to Obesity and Metabolic Disorders

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
The rising global incidence of obesity cannot be fully explained within the context of traditional risk factors such as an unhealthy diet, physical inactivity, aging, or genetics. Adipose tissue is an endocrine as well as a metabolic organ that may be susceptible to disruption by environmental estrogenic chemicals.
Mayur Doke, Vincent Avecilla, Quentin Felty, Stephen H. Safe   +3 more
wiley   +1 more source

Synthesis and antitubercular activity of novel 4-arylalkyl substituted thio-, oxy- and sulfoxy-quinoline analogues targeting the cytochrome bc1 complex [PDF]

, 2023
A library of 4-substituted quinolines was synthesised based on the structural features of the privileged 4-(benzylthio)-6-methoxy-2-methylquinoline scaffold.
Allen, R, Brucoli, F, Murnane, R, Parish, T, Santana-Gomez, F, Tanna, S, Zloh, M   +6 more
core   +5 more sources

Stem Cell Tracking Technologies for Neurological Regenerative Medicine Purposes

Stem Cells International, Volume 2017, Issue 1, 2017., 2017
The growing field of stem cell therapy is moving toward clinical trials in a variety of applications, particularly for neurological diseases. However, this translation of cell therapies into humans has prompted a need to create innovative and breakthrough methods for stem cell tracing, to explore the migration routes and its reciprocity with ...
Yongtao Zheng, Jiongwei Huang, Tongming Zhu, Ronggang Li, Zhifu Wang, Fukai Ma, Jianhong Zhu, Yao Li   +7 more
wiley   +1 more source

Sildenafil in the treatment of pressure ulcer: a randomised clinical trial

International Wound Journal, Volume 12, Issue 1, Page 111-117, February 2015., 2015
Abstract Pressure ulcer (PrU)‐related hospitalisation and mortality are critical issues in medical and surgical patients. Although animal studies have suggested the beneficial effects of sildenafil on wound healing, related clinical data are lacking. This is the first clinical study that has evaluated the effects of topical sildenafil on PrU healing in
Shadi Farsaei, Hossein Khalili, Effat S Farboud, Zahra Khazaeipour   +3 more
wiley   +1 more source

Synthesis of 5-oxyquinoline derivatives for reversal of multidrug resistance

Beilstein Journal of Organic Chemistry, 2012
The inhibition of ABC (ATP binding cassette) transporters is considered a powerful tool to reverse multidrug resistance. Zosuquidar featuring a difluorocyclopropyl-annulated dibenzosuberyl moiety has been found to be an inhibitor of the P-glycoprotein ...
Torsten Dittrich, Nils Hanekop, Nacera Infed, Lutz Schmitt, Manfred Braun   +4 more
doaj   +1 more source

Noneczematous Contact Dermatitis

International Scholarly Research Notices, Volume 2013, Issue 1, 2013., 2013
Irritant or allergic contact dermatitis usually presents as an eczematous process, clinically characterized by erythematoedematovesicous lesions with intense itching in the acute phase. Such manifestations become erythematous‐scaly as the condition progresses to the subacute phase and papular‐hyperkeratotic in the chronic phase.
Domenico Bonamonte, Caterina Foti, Michelangelo Vestita, Gianni Angelini, D. C. Cara, B. F. Gibbs, Y. L. Ye, Z. Zhu   +7 more
wiley   +1 more source

Leukocytosis of Unknown Origin: Gangrenous Cholecystitis

Case Reports in Medicine, Volume 2013, Issue 1, 2013., 2013
There have been case reports where patients admitted with acute cholecystitis, who were managed conservatively, had subsequently developed GC (gangrenous cholecystitis). The current case is unique, since our patient denied any prior episodes of abdominal pain and the only tip off was leukocytosis.
Amara Jyothi Nidimusili, M. Chadi Alraies, Naseem Eisa, Abdul Hamid Alraiyes, Khaldoon Shaheen, Gianfranco D. Alpini   +5 more
wiley   +1 more source

Antimicrobial Peptides as Infection Imaging Agents: Better Than Radiolabeled Antibiotics

International Journal of Peptides, Volume 2012, Issue 1, 2012., 2012
Nuclear medicine imaging techniques offer whole body imaging for localization of number and site of infective foci inspite of limitation of spatial resolution. The innate human immune system contains a large member of important elements including antimicrobial peptides to combat any form of infection.
Muammad Saeed Akhtar, Muhammad Babar Imran, Muhammad Afzal Nadeem, Abubaker Shahid, Mirian A. F. Hayashi   +4 more
wiley   +1 more source

Molecular SPECT Imaging: An Overview

International Journal of Molecular Imaging, Volume 2011, Issue 1, 2011., 2011
Molecular imaging has witnessed a tremendous change over the last decade. Growing interest and emphasis are placed on this specialized technology represented by developing new scanners, pharmaceutical drugs, diagnostic agents, new therapeutic regimens, and ultimately, significant improvement of patient health care.
Magdy M. Khalil, Jordi L. Tremoleda, Tamer B. Bayomy, Willy Gsell, Hiroshi Watabe   +4 more
wiley   +1 more source

Review on catalytic cleavage of C-C inter-unit linkages in lignin model compounds: Towards lignin depolymerisation [PDF]

, 2018
Lignin depolymerisation has received considerable attention recently due to the pressing need to find sustainable alternatives to fossil fuel feedstock to produce chemicals and fuels.
A Brandt, A Guerra, A Pineda, A Rahimi, A Sakakibara, A Toledano, A Wu, A Yamaguchi, AG Vishtal, AJ Ragauskas, AL Jongerius, B Biannic, B Ramírez-wong, B Sedai, B Sedai, B Sedai, BC Ahvazi, C Crestini, C Diaz-Urrutia, C Díaz-Urrutia, C Li, C Xu, C Zhu, CO Tuck, CP Kubicek, CS Lancefield, D Plackett, DJ Nicholson, DW Cho, DW Cho, E Amadio, E Windeisen, EE Harris, F Cavani, F Cherubini, F Cotana, F Napoly, F-X Luo, FG Calvo-Flores, FH Isikgor, FS Chakar, G Zhu, G Zhu, GW Huber, H Lange, H Wang, HE Schoemaker, J Dai, J Lupoi, J Mottweiler, J Popp, J Ralph, J Rencoret, J Zakzeski, J Zakzeski, J-b Huang, JH Clark, JJ Bozell, JK Glenn, JK Saini, K-S Shin, KE Hammel, L Shuai, L Shuai, LJ Mitchell, LM Kline, M Besson, M Chui, M Fasching, M Shimada, M Tien, M Wang, M Wang, Meenakshisundaram Sankar, MM Hepditch, MP Pandey, N Berezina, N-EE Mansouri, ND Patil, OY Abdelaziz, P Kaparaju, P Thompson, PJ Harvey, R Behling, R Ma, R Parthasarathi, R Rinaldi, RG Miller, RW Thring, S Birch, S Constant, S Kang, S Laurichesse, SK Hanson, SK Hanson, SK Hanson, Susana Guadix-Montero, T Renders, T Stein vom, W Boerjan, Y Ma, Y Matsushita   +101 more
core   +2 more sources