Prolactin and oxytocin: potential targets for migraine treatment
Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully understood. Besides the role of inflammatory mediators that interact with the trigeminovascular system, cyclic fluctuations in sex steroid hormones are involved in ...
Anna K. Szewczyk +18 more
doaj +1 more source
Effect of exogenous oxytocin on the expression of oxytocin receptor gene and uterine involution in local Iraqi cows [PDF]
The present work aimed to study the effect of exogenous oxytocin injection on the expression of the oxytocin receptor gene and the duration of uterine involution in the local Iraqi breed of Karradi cows. Twenty cows were divided into two groups.
Barra D. Al-Watar, Khawla A. Hussein
doaj +1 more source
Central mechanisms mediating the hypophagic effects of oleoylethanolamide and N-acylphosphatidylethanolamines: different lipid signals? [PDF]
The spread of "obesity epidemic" and the poor efficacy of many anti-obesity therapies in the long-term highlight the need to develop novel efficacious therapy. This necessity stimulates a large research effort to find novel mechanisms controlling feeding
Gaetani, Silvana +4 more
core +2 more sources
Anxious to see you: Neuroendocrine mechanisms of social vigilance and anxiety during adolescence. [PDF]
Social vigilance is a behavioral strategy commonly used in adverse or changing social environments. In animals, a combination of avoidance and vigilance allows an individual to evade potentially dangerous confrontations while monitoring the social ...
Cassano G. B. +6 more
core +1 more source
An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats
The hypothalamic neuropeptide oxytocin exerts analgesic effects, but the underlying pathways remain largely elusive. Here, the authors describe an analgesic pathway formed by oxytocin neurons projecting to the periaqueductal grey, where axonally released
Mai Iwasaki +30 more
doaj +1 more source
UNDULY ENHANCED RESPONSE TO TOLVAPTAN IN A WOMAN SHOWING SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION: AN INVESTIGATION OF POSSIBLE CAUSES [PDF]
Objective: To investigate possible causes of an excessive response to tolvaptan in a woman with syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Lanzellotti, Davide +4 more
core +1 more source
Oxytocin reduces adipose tissue inflammation in obese mice
Background Obesity and adipose tissue expansion is characterized by a chronic state of systemic inflammation that contributes to disease. The neuropeptide, oxytocin, working through its receptor has been shown to attenuate inflammation in sepsis, wound ...
Angela Szeto +4 more
doaj +1 more source
Labor-associated gene expression in the human uterine fundus, lower segment, and cervix [PDF]
Background Preterm labor, failure to progress, and postpartum hemorrhage are the common causes of maternal and neonatal mortality or morbidity. All result from defects in the complex mechanisms controlling labor, which coordinate changes in the ...
Aguan +37 more
core +3 more sources
Microbial lysate upregulates host oxytocin [PDF]
Neuropeptide hormone oxytocin has roles in social bonding, energy metabolism, and wound healing contributing to good physical, mental and social health. It was previously shown that feeding of a human commensal microbe Lactobacillus reuteri (L.
Alm, Eric J. +13 more
core +1 more source
The neurohormone oxytocin regulates many aspects of physiology primarily by binding to its receptor, the oxytocin receptor. The oxytocin receptor gene (Oxtr) has been shown to have alternative transcripts in the mouse brain which may each have different ...
Joshua S. Danoff +11 more
doaj +1 more source

