Results 151 to 160 of about 54,143 (245)

1,8-Cineole inhibits platelet-leukocyte aggregate formation by reducing P-selectin expression. [PDF]

Front Pharmacol
Petry J, Mai H, Shoykhet M, Bashiri Dezfouli A, Wollenberg B.   +4 more
europepmc   +1 more source

Thromboinflammatory biomarkers in obstetric pathophysiology: Predictive insights into placental insufficiency and feto‐maternal adverse outcomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Synergistic Efficacy of WST11-VTP and P-Selectin-Targeted Nanotherapy in a Preclinical Prostate Cancer Model. [PDF]

Cancers (Basel)
Nogueira L, Alvim R, Baker H, Nagar K, Thomas J, Alvim L, Kim K, Heller DA, Reis A, Scherz A, Coleman J.   +10 more
europepmc   +1 more source

Vector‐based comparison as a novel framework for assessing multi‐endpoint clinical trials: Applications to actual data

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Multi‐endpoint clinical trials face long‐standing statistical challenges. Vector‐based comparison (VBC) decomposes endpoints into orthogonal components. Applied to five clinical trials, it reduced confidence‐interval widths by about 50%, indicating higher statistical power, without altering the clinical meaning of endpoints.
Maria Kokkali, Vangelis D. Karalis
wiley   +1 more source

Acute pain in pediatric patients with SCD without chronic pain is associated with elevated VCAM-1 and P-selectin adhesion. [PDF]

Blood Vessel Thromb Hemost
Martin OY, Borhan R, Zaidi AU, Gao X, Ribbiso K, Darbari DS, Hines PC, Campbell AD.   +7 more
europepmc   +1 more source

Pulsed Electric Field Processing Enhances the Endothelial Bioefficacy of Red Beet (Beta vulgaris L.) Extracts by Restoring Endothelial Nitric Oxide Synthase–Nitric Oxide Signaling in High‐Fat Diet Rats

eFood, Volume 7, Issue 4, August 2026.
Pulsed electric field (PEF) processing qualitatively reshapes the phytochemical profile of red beet extracts, resulting in enhanced endothelial bioefficacy. Compared with conventional extraction, PEF‐treated extracts more effectively restore nitric oxide signaling, suppress endothelial inflammation, and normalize vascular structure in high‐fat diet ...
Eunju Jang, Tae‐Baek Lee, Lisa Tonini, Soobin Choi, YoonA Jeon, Taehyun Kim, Taeyoung Kang, Hyuk‐Joon Choi, Changhwan Ahn   +8 more
wiley   +1 more source

Correction: 1,8-Cineole inhibits platelet-leukocyte aggregate formation by reducing P-selectin expression. [PDF]

Front Pharmacol
Petry J, Mai H, Shoykhet M, Bashiri Dezfouli A, Wollenberg B.   +4 more
europepmc   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

P-Selectin Glycoprotein Ligand (PSGL)-1 Expression on CD4⁺ T Cells in Patients with HIV: Insights from an Observational Study. [PDF]

Pathogens
Zaongo SD, Wan Y, Zhang L, Tang S, Harypursat V, Chen Y.   +5 more
europepmc   +1 more source

Tumour‐Derived Extracellular Vesicles Containing dsRNA Induce Degradation of Ribosomal Protein mRNA in Platelets

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
ABSTRACT Extracellular vesicles (EVs) mediate intercellular communication within the tumour microenvironment by carrying cargoes from paracrine parent cells. EVs have attracted great research interest for their ability to carry nucleic acids into recipient cells and modulate cellular functions.
Gaoge Sun, Yuhuan Tao, Zihan Liu, Kaixiang Zhang, Shuai Zuo, Shanwen Chen, Shufang Ning, Tianyi Zhang, Pengyuan Wang, Ying Zhang, Zhi John Lu, Hang Hubert Yin   +11 more
wiley   +1 more source