Cyclophosphamide (CYP) alters the redox status in platelets, resulting in oxidative damage and platelet dysfunction as a result of oxidative stress. Melatonin plays a protective role and mitigates the CYP‐induced oxidative stress by directly scavenging ROS and augmenting the antioxidant defenses.
Anusha Berikai Ananthakrishna +2 more
wiley +1 more source
Aberrant engagement of P-selectin drives hematopoietic stem cell aging in mice. [PDF]
Yang D +11 more
europepmc +1 more source
Nanoparticle‐Mediated Therapy for Glioma: Advances and Prospects
Various nanocarriers, including liposomes, dendrimers, exosomes and gold nanoparticles, are designed to penetrate the blood‐brain barrier and deliver chemotherapy, radiotherapy, immunotherapy, gene therapy, phototherapy, magnetic hyperthermia and sonodynamic therapy for glioma.
Wenqian Jiang +5 more
wiley +1 more source
Ultrasound-activated and P-selectin-targeted liposomes overcome biofilm barriers for surgical site infections therapy. [PDF]
Liu X +10 more
europepmc +1 more source
Artificial Catch Bonds: From Molecular Design to Network Mechanics
Catch bonds strengthen rather than weaken under force. This review follows the discovery and development of our understanding of this counterintuitive phenomenon, from the molecular mechanisms that produce it to the design rules for engineering it in DNA, proteins, and polymers, and on to the collective network mechanics enabling materials that stiffen
Hengfeng Jiang +2 more
wiley +1 more source
Research Progress on <i>Salvia miltiorrhiza</i> Bioactive Components Regulating P-Selectin for Microcirculatory Improvement: Potential Implications in Acute Pancreatitis. [PDF]
Liu Y +9 more
europepmc +1 more source
Endothelial Function Is Associated With Incident Diabetes Mellitus: The ELSA‐Brasil Cohort Study
ABSTRACT Aims Diabetes mellitus is associated with endothelial dysfunction, but the bidirectional nature of this relationship remains debated. We aimed to evaluate the association between microvascular endothelial function and incident diabetes in Brazilian adults and to assess potential effect modification by obesity status.
Karina P. M. P. Martins +7 more
wiley +1 more source
Retraction Note: The P-selectin and PSGL-1 axis accelerates atherosclerosis via activation of dendritic cells by the TLR4 signaling pathway. [PDF]
Ye Z +7 more
europepmc +1 more source
Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai +2 more
wiley +1 more source

