Results 111 to 120 of about 80,651 (264)

Effects of sevoflurane and propofol anesthesia on intraoperative endothelial cell function in patients undergoing laparoscopic cholecystectomy

open access: yesJournal of International Medical Research, 2020
Objectives To investigate the effects of sevoflurane and propofol anesthesia on inflammatory or anti-inflammatory responses in patients undergoing laparoscopic cholecystectomy (LC). Methods Patients undergoing LC (n = 23) were divided into sevoflurane (S)
Yu Fan, Hao Wang, Qi Ma
doaj   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon   +5 more
wiley   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

open access: yesiNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong   +5 more
wiley   +1 more source

Angiogenesis, Inflammation, Platelets Count, and Metastatic Status as a Predictor for Thrombosis Risk in Nasopharyngeal Carcinoma Patients

open access: yesActa Medica Indonesiana, 2015
Aim: to assess the use of of angiogenesis, inflammation, platelets count, and metastatic status as predictors for thrombosis risk represented by soluble P-selectin level in nasopharyngeal carcinoma (NPC) patients.
Aru W Sudoyo   +2 more
doaj   +2 more sources

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

Differences of Main Levels of Serum P-Selectin and Trombosite in Severe Preeclampsia and Eclampsia

open access: yesAndalas Obstetrics and Gynecology Journal, 2017
Preeclampsia-eclampsia is a main complication of pregnancy in which the incidence is increasing world-wide and is associated with maternal morbidity and mortality.
Joserizal Serudji   +2 more
doaj   +1 more source

P-Selectin and Blood Coagulation [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2005
Although P-selectin had already been established as a vascular adhesion molecule critical in the inflammatory response, in 1992 Palabrica et al were the first to demonstrate that P-selectin also played a significant role in blood coagulation and thrombosis.1 In these experiments using an arteriovenous shunt model of thrombosis in a baboon, anti–P ...
openaire   +1 more source

Clinical Interpretation of Platelet Activation Marker sCLEC‐2 in Antiphospholipid Syndrome

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Soluble C‐type lectin‐like receptor 2 (sCLEC‐2), a marker of platelet activation, was evaluated in patients with antiphospholipid syndrome (APS). Plasma sCLEC‐2 levels and the sCLEC‐2/D‐dimer ratio were significantly elevated in APS compared with other collagen diseases and healthy controls.
Risa Kaneshige   +3 more
wiley   +1 more source

P-selectin

open access: yes
Citation: 'P-selectin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13531 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

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