Results 121 to 130 of about 80,651 (264)
VIEW, EarlyView.We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
P-selectin levels in women with endometriosis and non-endometriosis
Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2017 The discovery of a decline in the cellular immune system in endometrial tissue of women with endometriosis triggers the idea that immunologic factors may play a role in the process of endometriosis.
Tonny Simarmata
doaj
Applied SciencesInflammatory Bowel Disease (IBD) is a group of chronic intestinal diseases, among which Crohn’s disease (CD) and ulcerative colitis (UC) represent the two main types.
Aleksandra Górecka +5 more
doaj +1 more source
Advances in Hematology, 2018 Introduction. Inflammation is widely recognized to play an important role in cancer progression and is related to thrombosis. Soluble P-selectin (sP-selectin) is one of several biomarkers that may be predictive of thrombosis in cancer.
Adi Surya Komala, Andhika Rachman
doaj +1 more source
Multimodal Assessment of Kidney Quality During 24‐h of Normothermic Machine Perfusion
Artificial Organs, EarlyView.Normothermic machine perfusion (NMP) has emerged as a promising tool for assessing kidney quality prior to transplantation; however, reliable biomarkers remain to be established. In this study, thirteen porcine kidneys were perfused for 24 h using an autologous leukocyte‐filtered whole blood‐based perfusate applying urine recirculation.
Marlene Pühringer +22 more
wiley +1 more source
British Journal of Haematology, EarlyView.Fostamatinib had 46% durable response, with 73% steroid reduction, in this multicentre retrospective study of refractory wAIHA/ES. Hypertension, gastrointestinal (GI) distress and neutropenia occurred in 23%. Only one patient required drug discontinuation and one patient dose reduction.
Jorge N. Ruiz Lopez +16 more
wiley +1 more source
Inflammation and endothelial activation in benign prostatic hyperplasia and prostate cancer
International Brazilian Journal of Urology, 2011 PURPOSE: Emerging insights underline a link among chronic inflammation and endothelial activation with benign prostatic hyperplasia (BPH) and prostate cancer (PCa).
Gianna Pace +4 more
doaj +1 more source
British Journal of Haematology, EarlyView.Summary Follicular lymphoma (FL) first‐line chemoimmunotherapy yields high efficacy but serious toxicity in 65% of patients. In high tumour burden treatment‐naïve FL, we aimed to exploit known immunostimulatory and cytotoxic properties of combination checkpoint inhibition (atezolizumab) and obinutuzumab (6 cycles) with positron emission tomography (PET)
Arina Martynchyk +15 more
wiley +1 more source
Thrombocyta aktiváció során bekövetkező változások biokémiai és sejtbiológiai jellemzés = Biochemical and cell biological changes during platelet activation [PDF]
, 2009 Ex vivo mintákon végzett analízisek közül elvégeztük 30 db stent beültett beteg esetében perifáriás vérminták analízisét az alábbi thrombocyta aktivációs markerekre: thrombocyta P-selectin, solubilis P-selectin, CD63 expresszió, heterotipikus ...
Erdődi, Ferenc +4 more
core
British Journal of Haematology, EarlyView.Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov +15 more
wiley +1 more source