Results 121 to 130 of about 53,857 (243)

Concurrent P-Selectin Targeting Nanoparticle Orchestrates Tumor-Immune Dynamics for Advanced Immunochemotherapy. [PDF]

ACS Nano
Lee W, Lin SL, Chen JY, Huang BJ, Chieng WW, Tsai IJ, Chang TY, Lai YH, Hong WZ, Huang KC, Hung MC, Chen SY, Jeng LB, Shyu WC, Chiang CS.   +14 more
europepmc   +1 more source

Positive and Negative Cardiovascular Effects of JAK Inhibitors in Inflammation

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Chronic inflammation, characteristic of many autoimmune diseases, such as rheumatoid arthritis (RA), or myeloproliferative neoplasms (MPNs), is an independent driver of accelerated cardiovascular (CV) risk, primarily through proinflammatory cytokines that induce atherosclerosis and endothelial dysfunction.
Aliki Zavoriti, Pierre Miossec
wiley   +1 more source

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

Advanced Science, Volume 13, Issue 31, 4 June 2026.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller, Amelie Maribel Schneider, Ellen Sjule, Renhua Sun, Xiao Han, Luca Andronico, Edward Jenkins, Michael Dustin, Adnane Achour, Erdinc Sezgin   +9 more
wiley   +1 more source

Association of Umbilical Cord Blood P-Selectin and PTX3 Levels with Early-Onset Sepsis in Preterm Infants with Premature Rupture of Membranes. [PDF]

Int J Gen Med
Luo Y, Li M, Liu W, Xiu W.
europepmc   +1 more source

PRMT5/Sohlh2/Sirt1 Signaling Pathway in Vascular Endothelial Cells Modulates Lung Metastasis of Triple‐Negative Breast Cancer

Advanced Science, Volume 13, Issue 31, 4 June 2026.
The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang, Fengqin Wang, Lanlan Liu, Qi Zhang, Xiaoning Huo, Yanhui Nan, Yanli Dong, Yunling Xiao, Jing Hao   +8 more
wiley   +1 more source

P selectin promotes SARS-CoV-2 interactions with platelets and the endothelium. [PDF]

J Clin Invest
Moreno CL, Castanheira FV, Ospina Stella A, Chung F, Aggarwal A, Cole AJ, Loo L, Dupuy A, Kong YX, Hagimola L, Fenwick J, Coleman PR, Carr R, Du TY, Ison T, Newton M, Bui-Marinos MP, Cohen SB, Corcoran JA, Hesselson D, Gamble JR, Passam FH, Turville SG, Kubes P, Neely GG.   +24 more
europepmc   +1 more source

P-Selectin Measurement [PDF]

, 2020
openaire   +1 more source

A Cooperative Release of Mitochondrial DNA From Platelets and Neutrophils Drives an Interferon Signature in Systemic Sclerosis

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1281-1293, June 2026.
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis, André N. Tiaden, Simone Häner‐Massimi, Diego Kyburz, Cedric André, Anton Glück, Enrico Ferrero, Stuart Hawtin, Tobias Junt, Ulrich A. Walker   +9 more
wiley   +1 more source

Cell deformability enhances adhesion of ATRA-differentiated HL-60 cells to P-selectin. [PDF]

Eur J Med Res
Luo X, Li Q, Yang B, Zhuo P, Shen Y, Li J, Zhang F.   +6 more
europepmc   +1 more source

P-Selectin de-ACTIVation in COVID-19: What Have We Learned? [PDF]

Circulation, 2023
Bikdeli B, Eikelboom JW.
europepmc   +1 more source