Results 181 to 190 of about 54,143 (245)

Tumor-educated-platelets interact with breast cancer-stem-cells via P-selectin-PSGL1 and ensure stemness and metastasis through WNT-β-catenin-VEGF-VEGFR2 intra-cellular signaling: therapeutic modulation by aspirin. [PDF]

Breast Cancer Res
Guha A, Sultana J, Bhuniya A, Chakravarti M, Bera S, Sarkar A, Dhar S, Choudhury PR, Das P, Das J, Ganguly N, Guha I, Bairagya D, Das T, Alam N, Ghosh I, Hajra S, Barik S, Mukherjee KK, Baral R, Bose A, Banerjee S.   +21 more
europepmc   +1 more source

Clinical and Genetic Characterization of 269 Patients With Suspected Inherited Platelet Disorders: The Padua Monocentric Experience

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 856-865, August 2026.
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari, Daniela Regazzo, Antonella Bertomoro, Anna Cerbo, Alessandro Galbiati, Elisabetta Cosi, Paolo Simioni   +6 more
wiley   +1 more source

Intact quantitation and evaluation of a PEG-glycosulfopeptide as a therapeutic P-selectin antagonist. [PDF]

RSC Adv
Park DD, Park SS, Dai E, Haller CA, Wong DJ, Wever WJ, Cummings RD, Chaikof EL.   +7 more
europepmc   +1 more source

Investigator‐Led Research to Improve the Diagnostic Assessment of Platelet Function Disorders: Reflections on the Challenges and Rewards

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 721-731, August 2026.
ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley   +1 more source

The changing epidemiology of human type 2 diabetes–associated atherosclerosis: Pathophysiological mechanisms and emerging treatment possibilities

Journal of Internal Medicine, Volume 300, Issue 2, Page 131-152, August 2026.
Abstract Type 2 diabetes (T2D) is a major global health concern strongly associated with atherosclerosis and subsequent macrovascular complications. These complications are the leading cause of death among T2D patients. Despite a decline in cardiovascular events over the last decade, individuals with T2D still have an approximately doubled risk ...
Dania Al‐Sharify, Jiangming Sun, Andreas Edsfeldt   +2 more
wiley   +1 more source

The role of P-selectin/PSGL-1 in regulating NETs as a novel mechanism in cerebral ischemic injury. [PDF]

Front Neurol
Li X, Ma Y, Wang D.
europepmc   +1 more source

Targeting the P-selectin/PSGL-1 pathway: discovery of disease-modifying therapeutics for disorders of thromboinflammation. [PDF]

Blood Vessel Thromb Hemost
Escopy S, Chaikof EL.
europepmc   +1 more source

Comparative Analysis of P-selectin Levels in Psoriasis, Vitiligo, and Nonskin Disease in a Tertiary Care Hospital: A Case-Control Study. [PDF]

Ann Afr Med
Kumar J, Tiwari S, Suvirya S, Verma N, Chaudhary M, Gupta SK.   +5 more
europepmc   +1 more source

Synthetic Retinoid Sulfarotene Selectively Inhibits Tumor-Repopulating Cells of Intrahepatic Cholangiocarcinoma via Disrupting Cytoskeleton by P-Selectin/PSGL1 N-Glycosylation Blockage. [PDF]

Adv Sci (Weinh)
Du X, Qi Z, Chen S, Wu J, Xu Y, Hu S, Yu Z, Hou J, Fang Y, Xia J, Cao X.   +10 more
europepmc   +1 more source