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Regulation of Function and Expression of P-Selectin
1995P-selectin is an adhesion receptor for leukocytes that is expressed on activated platelets and endothelial cells. The surface expression of P-selectin is tightly regulated through signals in the cytoplasmic domain that mediate sorting into secretory granules, internalization into coated pits, and targeting to lysosomes for degradation.
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[Expression and identification of recombinant P-selectin and P-selectin glycoprotein ligand-1].
Sheng li xue bao : [Acta physiologica Sinica], 2015P-selectin, one of the membrane proteins, expresses on platelet and endothelia and interacts with P-selectin glycoprotein ligand-1 (PSGL-1) on leukocyte membrane. This interaction mediates leukocytes rolling on endothelial membrane and then induces leukocyte recruitment to the site of infection or tissue injury. In the present study, we constructed the
Xin-Hui, Pei +2 more
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Soluble P-selectin in Diabetes
Thrombosis and Haemostasis, 1999Jilma, B., Fijnheer, R., Blann, A.D.
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L-Selectin Shedding Regulates Leukocyte Recruitment
Journal of Experimental Medicine, 2001Klaus Ley, Ley Klaus, Huo Yuqing
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L-Selectin from Human, but Not from Mouse Neutrophils Binds Directly to E-Selectin
Journal of Cell Biology, 1997Dietmar Vestweber +2 more
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