Results 11 to 20 of about 23,411 (243)

CXXC5 mitigates P. gingivalis-inhibited cementogenesis by influencing mitochondrial biogenesis. [PDF]

Cell Commun Signal, 2023
Abstract Background Cementoblasts are tooth-root surface-lining cells responsible for cementum formation (cementogenesis) and sensitive to Porphyromonas gingivalis stimulation. We have previously proved transcription factor CXXC-type zinc finger protein 5 (CXXC5) participates in cementogenesis.
Ma L, Wang H, Huang X, Huang H, Peng Y, Liu H, Wang X, Cao Z.   +7 more
europepmc   +4 more sources

Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis [PDF]

International Immunopharmacology, 2009
Antibody titers to P. gingivalis are increased in patients with rheumatoid arthritis and are associated with disease-specific autoimmunity.Periodontitis (PD) has been implicated as a risk factor for rheumatoid arthritis (RA). We sought to characterize antibody titers to P.
Ted R, Mikuls, Jeffrey B, Payne, Richard A, Reinhardt, Geoffrey M, Thiele, Eileen, Maziarz, Amy C, Cannella, V Michael, Holers, Kristine A, Kuhn, James R, O'Dell   +8 more
openaire   +2 more sources

Curry Leaf Triggers Cell Death of P. gingivalis with Membrane Blebbing. [PDF]

Pathogens, 2021
Periodontal disease has become a serious public health problem, as indicated by accumulating evidence that periodontal disease is not only a major cause of tooth loss but is also associated with various systemic diseases. The present study assessed the anti-bacterial activities of three herbal products (curry leaf, clove, and cinnamon) against ...
Nakao R, Ikeda T, Furukawa S, Morinaga Y.   +3 more
europepmc   +5 more sources

Predicting Key Genes and Therapeutic Molecular Modelling to Explain the Association between Porphyromonas gingivalis (P. gingivalis) and Alzheimer's Disease (AD). [PDF]

Int J Mol Sci, 2023
The association between Porphyromonas gingivalis (P. gingivalis) and Alzheimer’s disease (AD) remains unclear. The major aim of this study was to elucidate the role of genes and molecular targets in P. gingivalis-associated AD. Two Gene Expression Omnibus (GEO) datasets, GSE5281 for AD (n = 84 Alzheimer’s, n = 74 control) and GSE9723 (n = 4 P ...
Hamarsha A, Balachandran K, Sailan AT, Nasruddin NS.   +3 more
europepmc   +3 more sources

Localization of P. gingivalis in Preterm Delivery Placenta [PDF]

Journal of Dental Research, 2009
Increasing evidence suggests an association between periodontal disease and adverse pregnancy outcomes. Although infection is considered as a risk factor for preterm delivery, the localization of oral bacteria or their antigens in chorioamnionitis placental tissue has never been demonstrated.
J, Katz, N, Chegini, K T, Shiverick, R J, Lamont   +3 more
openaire   +2 more sources

Extracellular vesicles of P. gingivalis-infected macrophages induce lung injury

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2021
Periodontal diseases are common inflammatory diseases that are induced by infection with periodontal bacteria such as Porphyromonas gingivalis (Pg). The association between periodontal diseases and many types of systemic diseases has been demonstrated; the term "periodontal medicine" is used to describe how periodontal infection/inflammation may impact
Kayo Yoshida, Kaya Yoshida, Natsumi Fujiwara, Mariko Seyama, Kisho Ono, Hotaka Kawai, Jiajie Guo, Ziyi Wang, Yao Weng, Yaqiong Yu, Yoko Uchida-Fukuhara, Mika Ikegame, Akira Sasaki, Hitoshi Nagatsuka, Hiroshi Kamioka, Hirohiko Okamura, Kazumi Ozaki   +16 more
openaire   +2 more sources

Intracellular Porphyromonas gingivalis Promotes the Proliferation of Colorectal Cancer Cells via the MAPK/ERK Signaling Pathway

Frontiers in Cellular and Infection Microbiology, 2020
Porphyromonas gingivalis (P. gingivalis) is a keystone pathogen in periodontitis. However, several clinical studies have revealed an enrichment of P. gingivalis in the stool samples and colorectal mucosa of colorectal cancer patients.
Wenxin Mu, Yiqun Jia, Xiaobing Chen, Haoyu Li, Zhi Wang, Bin Cheng   +5 more
doaj   +1 more source

P. gingivalis Modulates Keratinocytes through FOXO Transcription Factors

PLoS ONE, 2013
P. gingivalis is a prominent periodontal pathogen that has potent effects on host cells. In this study we challenged gingival epithelial cells with P. gingivalis with the aim of assessing how mRNA levels of key target genes were modulated by P. gingivalis via the transcription factors FOXO1 and FOXO3.
Li, Shuai, Dong, Guangyu, Moschidis, Anastasios, Ortiz, Javier, Kinane, Denis F, Benakanakere, Manjunatha R, Graves, Dana T   +6 more
openaire   +5 more sources

Roles of Oral Bacteria in Cardiovascular Diseases — From Molecular Mechanisms to Clinical Cases: Involvement of Porphyromonas gingivalis in the Development of Human Aortic Aneurysm

Journal of Pharmacological Sciences, 2010
Accumulating evidence suggests the involvement of Porphyromonas gingivalis (P. gingivalis), a periodontal pathogen, in cardiovascular diseases. Clinical specimens of aneurysmal tissue and dental plaque collected from patients infected with or without P ...
Koichiro Wada, Yoshinori Kamisaki
doaj   +1 more source

Inflammatory response of gut, spleen, and liver in mice induced by orally administered Porphyromonas gingivalis

Journal of Oral Microbiology, 2022
Background Periodontitis is a chronic multifactorial inflammatory disease. Porphyromonas gingivalis is a primary periopathogen in the initiation and development of periodontal disease. Evidence has shown that P.
Yingman Liu, Wenkai Huang, Ke Dai, Ni Liu, Jiaqi Wang, Xiaoying Lu, Jiaojiao Ma, Manman Zhang, Mengqi Xu, Xu Long, Jie Liu, Yurong Kou   +11 more
doaj   +1 more source