Results 21 to 30 of about 23,411 (243)

Antimicrobial and anti-inflammatory activity of Cystatin C on human gingival fibroblast incubated with Porphyromonas gingivalis [PDF]

PeerJ, 2022
Background Periodontal disease is considered one of the most prevalent chronic infectious diseases, often leading to the disruption of tooth-supporting tissues, including alveolar bone, causing tooth mobility and loss.
Blanca Esther Blancas-Luciano, Ingeborg Becker-Fauser, Jaime Zamora-Chimal, José Delgado-Domínguez, Adriana Ruíz-Remigio, Elba Rosa Leyva-Huerta, Javier Portilla-Robertson, Ana María Fernández-Presas   +7 more
doaj   +2 more sources

Development and evaluation of a saliva-based chair-side diagnostic for the detection of Porphyromonas gingivalis

Journal of Oral Microbiology, 2015
Porphyromonas gingivalis is a key pathogen in the polymicrobial biofilm that is associated with the oral disease chronic periodontitis. A number of studies have shown that in humans the level of P.
Neil M. O'Brien-Simpson, Kate Burgess, Gail C. Brammar, Ivan B. Darby, Eric C. Reynolds   +4 more
doaj   +1 more source

<i>P. gingivalis</i>-Infected Macrophage Extracellular Vesicles Cause Adverse Pregnancy Outcomes. [PDF]

J Dent Res
Periodontitis is a chronic inflammatory disease triggered by oral bacterial infection, with the bacterium Porphyromonas gingivalis being a major causative agent. The association between periodontitis and various systemic diseases has been demonstrated.
Tanai A, Fukuhara Y, Eguchi T, Kawai H, Ueda K, Ochiai K, Ikegame M, Okamoto K, Okamura H.   +8 more
europepmc   +3 more sources

LPS from P. gingivalis Negatively Alters Gingival Cell Mitochondrial Bioenergetics [PDF]

International Journal of Dentistry, 2017
Objective. Oral inflammatory pathologies are linked to increased oxidative stress, thereby partly explaining their relevance in the etiology of systemic disorders. The purpose of this work was to determine the degree to which LPS from Porphyromonas gingivalis, the primary pathogen related to oral inflammation, altered gingival mitochondrial function ...
Kiran Napa, Andrea C. Baeder, Jeffrey E. Witt, Sarah T. Rayburn, Madison G. Miller, Blake W. Dallon, Jonathan L. Gibbs, Shalene H. Wilcox, Duane R. Winden, Jared H. Smith, Paul R. Reynolds, Benjamin T. Bikman   +11 more
openaire   +3 more sources

Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase

International Journal of Oral Science, 2021
Ulcerative Colitis (UC) has been reported to be related to Porphyromonas gingivalis (P. gingivalis). Porphyromonas gingivalis peptidylarginine deiminase (PPAD), a virulence factor released by P. gingivalis, is known to induce inflammatory responses.
Xida Zhao, Jingbo Liu, Chong Zhang, Ning Yu, Ze Lu, Shuwei Zhang, Yuchao Li, Qian Li, Junchao Liu, Dongjuan Liu, Yaping Pan   +10 more
doaj   +1 more source

Host insulin resistance caused by Porphyromonas gingivalis-review of recent progresses

Frontiers in Cellular and Infection Microbiology, 2023
Porphyromonas gingivalis (P. gingivalis) is a Gram-negative oral anaerobic bacterium that plays a key role in the pathogenesis of periodontitis. P. gingivalis expresses a variety of virulence factors that disrupt innate and adaptive immunity, allowing P.
Shuxian Jia, Shuxian Jia, Xiaobing Li, Xiaobing Li, Qin Du   +4 more
doaj   +1 more source

Heme Competition Triggers an Increase in the Pathogenic Potential of Porphyromonas gingivalis in Porphyromonas gingivalis-Candida albicans Mixed Biofilm

Frontiers in Microbiology, 2020
As one of the main pathogens of periodontitis, Porphyromonas gingivalis often forms mixed biofilms with other bacteria or fungi under the gingiva, such as Candida albicans. Heme is an important iron source for P. gingivalis and C.
Yanyang Guo, Yu Wang, Yijin Wang, Yabing Jin, Chen Wang   +4 more
doaj   +1 more source

Porphyromonas gingivalis Gingipain-Dependently Enhances IL-33 Production in Human Gingival Epithelial Cells. [PDF]

PLoS ONE, 2016
The cytokine IL-33 is constitutively expressed in epithelial cells and it augments Th2 cytokine-mediated inflammatory responses by regulating innate immune cells.
Hiroyuki Tada, Takashi Matsuyama, Takashi Nishioka, Makoto Hagiwara, Yusuke Kiyoura, Hidetoshi Shimauchi, Kenji Matsushita   +6 more
doaj   +1 more source

Platelet aggregation promoted by biofilms of oral bacteria and the effect of mouth rinses in vitro

Journal of Infection in Developing Countries, 2016
Introduction: The purpose of this study was to observe platelet aggregation promoted by biofilms of Streptococcus sanguinis and Porphyromonas gingivalis and to evaluate the effect of two different mouth rinses on this process.
Yan Tu, Yadong Chen, Chongyang Zheng, Hui Chen   +3 more
doaj   +1 more source

Porphyromonas gingivalis -Specific Immunoglobulin G Prevents P. gingivalis -Elicited Oral Bone Loss in a Murine Model [PDF]

Infection and Immunity, 2004
ABSTRACT Active immunization with Porphyromonas gingivalis whole-cell preparations has been shown to prevent P. gingivalis infection and oral bone loss. Employing passive antibody transfer and opsonization, we demonstrate with this study that immunization-elicited P ...
Frank C, Gibson, Dario A, Gonzalez, Jodie, Wong, Caroline Attardo, Genco   +3 more
openaire   +2 more sources