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Produktion eines Derivats des antimikrobiellen Peptids NK-Lysin in E. coli und P. pastoris

Die stetige Zunahme antimikrobieller Resistenzen stellt eine erhebliche globale Bedrohung dar. Aufgrund dessen sind antimikrobielle Peptide als Alternative zu traditionellen Antibiotika in den Fokus der Pharmaindustrie gerückt. NK2-ALK, ein Derivat des antimikrobiellen Peptids NK-Lysin, zeigt eine hohe Aktivität gegenüber einem breiten Spektrum von ...
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Genome sequence of the recombinant protein production host Pichia pastoris

Nature Biotechnology, 2009
Kristof De Schutter   +2 more
exaly  

The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO2

Nature Biotechnology, 2019
Thomas Gassler   +2 more
exaly  

Characterization of the House Dust Mite Allergen, Der p 23 produced in Pichia pastoris.

Recent identified Der p 23 has been recognized as an important house dust mite (HDM) allergen which displays high IgE reactivity comparable to the major HDM allergens Der p 1 and Der p 2. Due to limited amounts of the natural allergen, the in-depth characterization of Der p 23 requires the production of a recombinant form.
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