Results 11 to 20 of about 57,540 (217)

Progress towards the development of a P. vivax vaccine [PDF]

Expert Review of Vaccines, 2021
Plasmodium vivax causes significant public health problems in endemic regions. A vaccine to prevent disease is critical, considering the rapid spread of drug-resistant parasite strains, and the development of hypnozoites in the liver with potential for relapse. A minimally effective vaccine should prevent disease and transmission while an ideal vaccine
Sai Lata, De, Francis B, Ntumngia, Justin, Nicholas, John H, Adams   +3 more
openaire   +4 more sources

Host metabolomic responses in recurrent P. vivax malaria [PDF]

Scientific Reports
AbstractMalaria is the leading parasitic disease worldwide, with P. vivax being a major challenge for its control. Several studies have indicated metabolomics as a promising tool for combating the disease. The study evaluated plasma metabolomic profiles of patients with recurrent and non-recurrent P. vivax malaria in the Brazilian Amazon.
Michael N. Yakubu, Victor I. Mwangi, Rebeca L. A. Netto, Maria G. C. Alecrim, Jessica R. S. Alves, Anne C. G. Almeida, Gabriel F. Santos, Gesiane S. Lima, Lucas S. Machado, Hector H. F. Koolen, Tiago P. Guimarães, Andrea R. Chaves, Boniek G. Vaz, Wuelton M. Monteiro, Fabio T. M. Costa, Marcus V. G. Lacerda, Luiz G. Gardinassi, Gisely C. de Melo   +17 more
openaire   +4 more sources

Epidemiological characteristics of P. vivax asymptomatic infections in the Peruvian Amazon [PDF]

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionHerein, we tested the hypothesis that Asymptomatic P. vivax (Pv) infected individuals (Asym) feature different epidemiological, clinical and biochemical characteristics, as well as hematological parameters, potentially predictive of clinical immunity in comparison to symptomatic Pv infected individuals (Sym).MethodologyBetween 2018 - 2021 ...
Elizabeth Villasis, Elizabeth Villasis, Stefano S. Garcia Castillo, Mitchel Guzman, Mitchel Guzman, Julian Torres, Joaquin Gomez, Katherine Garro, Ana Maria Cordova, Carolina Reategui, Caroline Abanto, Joseph Vinetz, Joseph Vinetz, Dionicia Gamboa, Dionicia Gamboa, Dionicia Gamboa, Katherine Torres, Katherine Torres   +17 more
openaire   +5 more sources

Molecular evidence of Plasmodium vivax mono and mixed malaria parasite infections in Duffy-negative native Cameroonians. [PDF]

PLoS ONE, 2014
The malaria parasite Plasmodium vivax is known to be majorly endemic to Asian and Latin American countries with no or very few reports of Africans infected with this parasite. Since the human Duffy antigens act as receptors for P.
Huguette Gaelle Ngassa Mbenda, Aparup Das   +1 more
doaj   +1 more source

Limited polymorphism in k13 gene of Plasmodium falciparum and k12 of Plasmodium vivax isolates imported from African and Asian countries between 2014 and 2019 in Hangzhou city, China

BMC Infectious Diseases, 2021
Background Malaria causes major public health problems globally and drug resistance hinders its control and elimination. Molecular markers associated with drug resistance are considered as a beneficial tool to monitor the disease trends, evolution and ...
Xingyi Jin, Sujuan Zhu, Weimin Xu, Junfang Chen, Wei Ruan, Xiaoxiao Wang   +5 more
doaj   +1 more source

SEROEPIDEMIOLOGICAL STUDY OF P. VIVAX MALARIA WITH SUSPECTED LONG INCUBATION IN IRAN [PDF]

Iranian Journal of Public Health, 1976
P. vivax malaria with suspected long incubation have been frequently observed mostly in the northwest part of Iran in the course of Malaria Control and Malaria Eradication Operations.
Gh. H. Edrissian, F. Naimi, A. Afshar
doaj   +2 more sources

Immunity to malaria in Plasmodium vivax infection: a study in central China. [PDF]

PLoS ONE, 2012
P. vivax infection is characterised by relapsing fever, indicating reinfection by previously hidden parasites in the host. Relapsed infection can lead to the activation of the memory T cell pool, which may lead to protective immunity.
Kulachart Jangpatarapongsa, Hui Xia, Qiang Fang, Kaiming Hu, Yuanying Yuan, Meiyu Peng, Qi Gao, Jetsumon Sattabongkot, Liwang Cui, Baiqing Li, Rachanee Udomsangpetch   +10 more
doaj   +1 more source

Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model [PDF]

, 2015
The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries.
Bassat, Quique, Betuela, Inoni, Brewster, Jessica, Felger, Ingrid, Hofmann, Natalie E., Karl, Stephan, Kinboro, Benson, Kiniboro, Benson, Li Wai Suen, Connie S. N., Lorry, Lina, Mueller, Ivo, Robinson, Leanne J., Samol, Lornah, Schofield, Louis, Siba, Peter M., Silkey, Mariabeth, Tarongka, Nandao, Waltmann, Andreea, Wampfler, Rahel, White, Michael T.   +19 more
core   +7 more sources

An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples. [PDF]

, 2015
BackgroundHighly sensitive, scalable diagnostic methods are needed to guide malaria elimination interventions. While traditional microscopy and rapid diagnostic tests (RDTs) are suitable for the diagnosis of symptomatic malaria infection, more sensitive ...
Adams, Matthew, Han, Kay Thwe, Han, Zay Yar, Hlaing, Tin Maung, Huang, Fang, Johnson, Nicole Eddington, Joshi, Sudhaunshu N, Mbambo, Gillian, Mu, Amy Z, Nyunt, Myaing M, Oo, Khine Zaw, Plowe, Christopher V, Richards, Adam K, Roemmich, Shay M, Shrestha, Biraj, Strauss, Kathy A, Thura, Si   +16 more
core   +2 more sources

Applied genomics: data mining reveals species-specific malaria diagnostic targets more sensitive than 18S rRNA. [PDF]

, 2011
Accurate and rapid diagnosis of malaria infections is crucial for implementing species-appropriate treatment and saving lives. Molecular diagnostic tools are the most accurate and sensitive method of detecting Plasmodium, differentiating between ...
Demas, Allison, Oberstaller, Jenna, DeBarry, Jeremy, Lucchi, Naomi W, Srinivasamoorthy, Ganesh, Sumari, Deborah, Kabanywanyi, Abdunoor M, Villegas, Leopoldo, Escalante, Ananias A, Kachur, S Patrick, Barnwell, John W, Peterson, David S, Udhayakumar, Venkatachalam, Kissinger, Jessica C   +13 more
core   +1 more source