Results 21 to 30 of about 27,075 (176)

In vitro and ex vivo antiplasmodial activity of 1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one) against circulating strains of Plasmodium spp. in the state of Rondônia, Brazil [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2023
Malaria is a disease caused by Plasmodium spp. protozoa. The ability of Plasmodium to develop resistance to current antimalarial drugs makes the study of chemotherapeutic alternatives extremely important.
Vanessa Margarida Vicentini, Welington da Silva Paula do Nascimento, Marcinete Latorre Almeida, Daniel Sol Sol de Medeiros, Ana Paula de Azevedo dos Santos, Joana D ‘Arc Neves Costa, Dhélio Batista Pereira, Mauro Shugiro Tada, Leonardo de Azevedo Calderon, Carolina Bioni Garcia Teles   +9 more
doaj   +1 more source

The diagnostic and prognostic value of conventional and rapid diagnostic tools in malaria [PDF]

Al Ameen Journal of Medical Sciences, 2016
Background: The burden of malaria is raising all over the world and India is no exception. Despite well established treatment regimens and diagnostic tools, Malaria is thought to kill between1.1 to 2.7 million people worldwide each year.
Chandrakanth C.H
doaj  

Using Plasmodium knowlesi as a model for screening Plasmodium vivax blood-stage malaria vaccine targets reveals new candidates.

PLoS Pathogens, 2021
Plasmodium vivax is responsible for the majority of malaria cases outside Africa. Unlike P. falciparum, the P. vivax life-cycle includes a dormant liver stage, the hypnozoite, which can cause infection in the absence of mosquito transmission.
Duncan N Ndegwa, Prasun Kundu, Jessica B Hostetler, Alejandro Marin-Menendez, Theo Sanderson, Kioko Mwikali, Lisa H Verzier, Rachael Coyle, Sophie Adjalley, Julian C Rayner   +9 more
doaj   +1 more source

High Rates of Asymptomatic, Sub-microscopic Plasmodium vivax Infection and Disappearing Plasmodium falciparum Malaria in an Area of Low Transmission in Solomon Islands. [PDF]

PLoS Neglected Tropical Diseases, 2015
INTRODUCTION:Solomon Islands is intensifying national efforts to achieve malaria elimination. A long history of indoor spraying with residual insecticides, combined recently with distribution of long lasting insecticidal nets and artemether-lumefantrine ...
Andreea Waltmann, Andrew W Darcy, Ivor Harris, Cristian Koepfli, John Lodo, Ventis Vahi, David Piziki, G Dennis Shanks, Alyssa E Barry, Maxine Whittaker, James W Kazura, Ivo Mueller   +11 more
doaj   +1 more source

Genomic analyses of complex P. vivax infections [PDF]

Malaria Journal, 2014
Results All field isolates sequenced so far show evidence of complex infections, with typically 2-4 strains present at >5%. We show that it is possible, empirically and analytically, to rigorously differentiate these parasites and reconstruct haploid genome sequences from these complex infections.
Chan, Ernest, Menard, Didier, Barnwell, John, Zimmerman, Peter, Serre, David   +4 more
openaire   +1 more source

Immune responses during gestational malaria: a review of the current knowledge and future trend of research

Journal of Infection in Developing Countries, 2014
Women pregnant with their first child are susceptible to severe P. falciparum disease from placental malaria because they lack immunity to placenta-specific cytoadherence proteins.
Amanda Maestre, Jaime Carmona-Fonseca
doaj   +1 more source

Geographical origin of Plasmodium vivax in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome

Malaria Journal, 2010
Background The Republic of Korea (South Korea) is one of the countries where vivax malaria had been successfully eradicated by the late 1970s. However, re-emergence of vivax malaria in South Korea was reported in 1993. Several epidemiological studies and
Iwagami Moritoshi, Hwang Seung-Young, Fukumoto Megumi, Hayakawa Toshiyuki, Tanabe Kazuyuki, Kim So-Hee, Kho Weon-Gyu, Kano Shigeyuki   +7 more
doaj   +1 more source

Ethiopian Plasmodium vivax hypnozoites formation dynamics and their susceptibility to reference antimalarial drugs

BMC Infectious Diseases, 2023
One of the key obstacles to malaria elimination is largely attributed to Plasmodium vivax’s ability to form resilient hypnozoites in the host liver that cause relapsing infections. As a result, interruption of P. vivax transmission is difficult. P. vivax
Laurent Dembele, Ousmaila Diakite, Fanta Sogore, Soriya Kedir, Fatalmoudou Tandina, Mohamed Maiga, Andargie Abate, Lemu Golassa, Abdoulaye A. Djimde   +8 more
doaj   +1 more source

The probability of a sequential Plasmodium vivax infection following asymptomatic Plasmodium falciparum and P. vivax infections in Myanmar, Vietnam, Cambodia, and Laos

Malaria Journal, 2019
Background Adding 8-aminoquinoline to the treatment of falciparum, in addition to vivax malaria, in locations where infections with both species are prevalent could prevent vivax reactivation.
Lorenz von Seidlein, Pimnara Peerawaranun, Mavuto Mukaka, Francois H. Nosten, Thuy-Nhien Nguyen, Tran Tinh Hien, Rupam Tripura, Thomas J. Peto, Tiengkham Pongvongsa, Koukeo Phommasone, Mayfong Mayxay, Mallika Imwong, James Watson, Sasithon Pukrittayakamee, Nicholas P. J. Day, Arjen M. Dondorp   +15 more
doaj   +1 more source

Evaluation of Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites as a Preerythrocytic P. vivax Vaccine

Clinical and Vaccine Immunology, 2017
ABSTRACT Four different vaccine platforms, each targeting the human malaria parasite Plasmodium vivax cell-traversal protein for ookinetes and sporozoites ( Pv CelTOS), were generated and assessed for protective efficacy.
Alves, E., Salman, A.M., Leoratti, F., Lopez-Camacho, C., Viveros-Sandoval, M.E., Lall, A., El-Turabi, A., Bachmann, M.F., Hill, A.V.S., Janse, C.J., Khan, S.M., Reyes-Sandoval, A.   +11 more
openaire   +5 more sources