Results 41 to 50 of about 57,540 (217)

Ethiopian Plasmodium vivax hypnozoites formation dynamics and their susceptibility to reference antimalarial drugs

BMC Infectious Diseases, 2023
One of the key obstacles to malaria elimination is largely attributed to Plasmodium vivax’s ability to form resilient hypnozoites in the host liver that cause relapsing infections. As a result, interruption of P. vivax transmission is difficult. P. vivax
Laurent Dembele, Ousmaila Diakite, Fanta Sogore, Soriya Kedir, Fatalmoudou Tandina, Mohamed Maiga, Andargie Abate, Lemu Golassa, Abdoulaye A. Djimde   +8 more
doaj   +1 more source

Contrasting epidemiology and genetic variation of Plasmodium vivax infecting Duffy-negative individuals across Africa

International Journal of Infectious Diseases, 2021
Objectives: Plasmodium vivax malaria was thought to be rare in Africans who lack the Duffy blood group antigen expression. However, recent studies indicate that P.
Eugenia Lo, Gianluca Russo, Kareen Pestana, Daniel Kepple, Beka Raya Abagero, Ghyslaine Bruna Djeunang Dongho, Karthigayan Gunalan, Louis H. Miller, Muzamil Mahdi Abdel Hamid, Delenasaw Yewhalaw, Giacomo Maria Paganotti   +10 more
doaj   +1 more source

Variation in relapse frequency and the transmission potential of Plasmodium vivax malaria [PDF]

, 2016
There is substantial variation in the relapse frequency of Plasmodium vivax malaria, with fast-relapsing strains in tropical areas, and slow-relapsing strains in temperate areas with seasonal ...
Ghani, A, Karl, S, Mueller, I, Shirreff, G, White, MT   +4 more
core   +4 more sources

The probability of a sequential Plasmodium vivax infection following asymptomatic Plasmodium falciparum and P. vivax infections in Myanmar, Vietnam, Cambodia, and Laos

Malaria Journal, 2019
Background Adding 8-aminoquinoline to the treatment of falciparum, in addition to vivax malaria, in locations where infections with both species are prevalent could prevent vivax reactivation.
Lorenz von Seidlein, Pimnara Peerawaranun, Mavuto Mukaka, Francois H. Nosten, Thuy-Nhien Nguyen, Tran Tinh Hien, Rupam Tripura, Thomas J. Peto, Tiengkham Pongvongsa, Koukeo Phommasone, Mayfong Mayxay, Mallika Imwong, James Watson, Sasithon Pukrittayakamee, Nicholas P. J. Day, Arjen M. Dondorp   +15 more
doaj   +1 more source

Evaluation of Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites as a Preerythrocytic P. vivax Vaccine

Clinical and Vaccine Immunology, 2017
ABSTRACT Four different vaccine platforms, each targeting the human malaria parasite Plasmodium vivax cell-traversal protein for ookinetes and sporozoites ( Pv CelTOS), were generated and assessed for protective efficacy.
Alves, E., Salman, A.M., Leoratti, F., Lopez-Camacho, C., Viveros-Sandoval, M.E., Lall, A., El-Turabi, A., Bachmann, M.F., Hill, A.V.S., Janse, C.J., Khan, S.M., Reyes-Sandoval, A.   +11 more
openaire   +6 more sources

Molecular typing reveals substantial Plasmodium vivax infection in asymptomatic adults in a rural area of Cameroon [PDF]

, 2014
BACKGROUND: Malaria in Cameroon is due to infections by Plasmodium falciparum and, to a lesser extent, Plasmodium malariae and Plasmodium ovale, but rarely Plasmodium vivax.
Innocent Safeukui, Jerome Fru-Cho, Kasturi Haldar, Theresa Nkuo-Akenji, Vincent PK Titanji, Violet V Bumah   +5 more
core   +1 more source

Heritability of P. falciparum and P. vivax Malaria in a Karen Population in Thailand

PLoS ONE, 2008
ركزت غالبية الدراسات المتعلقة بعلم الوراثة المضيفة للملاريا على الجينات الفردية التي تمنح الحماية ضد الملاريا بدلاً من التعرض لها. إن تحديد التأثير النسبي للعوامل الوراثية مقابل العوامل غير الوراثية على عدوى الملاريا ومرضها أمر ضروري لتركيز الجهود على العوامل المحددة الرئيسية.
Waraphon Phimpraphi, Paul Rácz, Bhee Witoonpanich, Chairat Turbpaiboon, Chayanon Peerapittayamongkol, Chalisa Louicharoen, Isabelle Casadémont, Sumalee Tungpradabkul, Srivicha Krudsood, Jaranit Kaewkunwal, Thanyachai Sura, Sornchai Looareesuwan, Pratap Singhasivanon, Anavaj Sakuntabhai   +13 more
openaire   +5 more sources

Declining malaria transmission in rural Amazon: changing epidemiology and challenges to achieve elimination [PDF]

, 2016
BACKGROUND: In recent years, considerable success in reducing its incidence has been achieved in Brazil, leading to a relative increase in the proportion of cases caused by Plasmodium vivax, considered a
Alonso, Pedro, Bassat Orellana, Quique, Guinovart, Caterina, Lacerda, Marcus Vinícius Guimarães, Melo, Gisely Cardoso de, Monteiro, Wuelton Marcelo, Portillo Obando, Hernando A. del, Reyes-Lecca, Roberto Carlos, Siqueira, André Machado, Souza Sampaio, Vanderson de, Vitor Silva, Sheila   +10 more
core   +1 more source

ACKR1/Duffy‐null genotype testing for clozapine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Clozapine is licenced for treatment‐resistant schizophrenia and psychosis in Parkinson's disease. In the United Kingdom, there is a mandatory requirement for absolute neutrophil count (ANC) and white blood cell count (WBC) monitoring to safeguard against agranulocytosis.
Stephen Murtough, Oriella Stellakis, Daisy Mills, Blanca Bjourson, Vicky Chaplin, Dharmisha Chauhan, Bev Chipp, Marius Cotic, Jana de Villiers, Olubanké Dzahini, Frances Elmslie, Katie Evans, Shreyans Gandhi, Dyfrig A. Hughes, Huajie Jin, Daniele Panconesi, Anna Skowronska, Sanjay M. Sisodiya, Ed Silva, Vicky Stinton, Sara Stuart‐Smith, Sarah Tarrant, David Taylor, Lauren Varney, James T. R. Walters, Michelle Wood, Jessica Woodley, Cinzia Dello Russo, Munir Pirmohamed, Elvira Bramon   +29 more
wiley   +1 more source

The Plasmodium vivax Merozoite Surface Protein 1 Paralog Is a Novel Erythrocyte-Binding Ligand of P. vivax [PDF]

Infection and Immunity, 2013
ABSTRACT Merozoite surface protein 1 of Plasmodium vivax (PvMSP1), a glycosylphosphatidylinositol-anchored protein (GPI-AP), is a malaria vaccine candidate for P. vivax . The paralog of PvMSP1, named P.
Yang, Cheng, Yue, Wang, Daisuke, Ito, Deok-Hoon, Kong, Kwon-Soo, Ha, Jun-Hu, Chen, Feng, Lu, Jian, Li, Bo, Wang, Eizo, Takashima, Jetsumon, Sattabongkot, Takafumi, Tsuboi, Eun-Taek, Han   +12 more
openaire   +2 more sources