Results 101 to 110 of about 89,060 (300)
Advanced Science, EarlyView.Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu +9 more
wiley +1 more source
, 2015 Representative p16 western blot of HPV-positive and -negative antrochoanal polyps (ACP), nasal polyps (NP), nasal turbinates (NT) and oropharyngeal carcinoma (OPC). Two HPV-positive carcinomas are showing strong p16 bands. Three of four HPV-positive.
Konstantin Tziridis (304601) +4 more
core +1 more source
Advanced Science, EarlyView.Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim +2 more
wiley +1 more source
Analiza mutacji p14 i p16 w czerniaku skóry
, 2011 Introduction. Cutaneous melanoma is a malignant tumour derivedfrom melanocytes that occurs primarily in the skin. It is a result of prolongedexposure to mutagenic factors and an abnormal DNA repairsystem.
Tadeusz Tadrowski +3 more
core
Australian Journal of Social Issues, EarlyView.ABSTRACT While Australia's National Disability Insurance Scheme (NDIS) was founded on principles of choice and control, for people with significant mental health challenges (what the NDIS calls ‘psychosocial disability’) these ideals often remain elusive. Support systems continue to be fractured and in the context of ongoing policy reforms, it is vital
Joel Hollier, Jennifer Smith‐Merry
wiley +1 more source
Oncotarget, 2013 Infections with high-risk human papillomaviruses (HPV) account for approximately 5% of all human cancers. Cervical cancer, in particular, is almost universally caused by “high-risk” HPV infections and these HPVs also cause a large fraction of other anogenital tract cancers as well as oral carcinomas.
Karl, Munger +2 more
openaire +2 more sources
Annals of Neurology, EarlyView.Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral +52 more
wiley +1 more source
Anais Brasileiros de Dermatologia, 2006 FUNDAMENTOS: A deleção e mutação do gene CDKN2a que codifica um inibidor específico da ciclina dependente de quinase 4, a proteína p16, têm sido implicadas na tumorigênese do melanoma cutâneo. Entretanto, pouco se conhece sobre essas alterações genéticas
Ricardo Hsieh +5 more
doaj +1 more source
Expression of p16 in Colorectal Cancer and its Comparison with Prognostic Parameters
, 2010 Aim: The cells are either in dividing or resting state. p 16 INK4a, arrests the cell cycle in late period of G1 stage, by inhibiting RB phosphorylation.
Mihriban Gürbüzel +2 more
core
Arthritis &Rheumatology, EarlyView.Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla +13 more
wiley +1 more source