Results 111 to 120 of about 210,208 (298)

Immunostaining for p53 and p16^CDKN2A Protein Is Not Predictive of Prognosis for Dogs with Malignant Mammary Gland Neoplasms

Veterinary Sciences, 2019
Mammary gland tumors (MGTs) are common in dogs and show a variable clinical behavior that is difficult to predict. Currently, few immunohistochemical markers have been established to predict the prognosis of a canine MGT.
John S Munday, Harsha Ariyarathna, Danielle Aberdein, Neroli A Thomson   +3 more
doaj   +1 more source

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications

Head &Neck, EarlyView.
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen, S. Mohsen Hosseini, Mark Zafereo, Miriam Lango, Elizabeth Gardner Grubbs, Priyanka Iyer, Shreyaskumar R. Patel, Vinod Ravi, Naifa Lamki Busaidy, Rui Jennifer Wang, Michelle D. Williams, Maria E. Cabanillas, Anastasios Maniakas   +12 more
wiley   +1 more source

Combined immunohistochemistry of PRAME and p16 in the differentiation of melanocytic neoplasms, with a detailed focus on acral lesions

Diagnostic Pathology
Background Isolated immunohistochemical indicators are limited to diagnose melanocytic neoplasms. This retrospective study is to assess the diagnostic value of combined immunohistochemical analysis targeting preferentially expressed antigen in melanoma ...
Jingwei Zheng, Jie Zang, Qiuju Miao, Xuebao Shao, Hao Song, Xiaopo Wang, Ying Zhang, Hao Chen   +7 more
doaj   +1 more source

Postoperative and Functional Outcomes of Oropharyngectomy in Irradiated Neck for Recurrent or Metachronous Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate predictors of postoperative and functional outcomes following salvage oropharyngectomy. Methods In this single‐center retrospective study, we included all patients who underwent an oropharyngectomy in an irradiated neck for recurrent or metachronous cancer between 2014 and 2023. Results We included 94 patients.
Jade Saykaly, Agnès Dupret‐Bories, Sébastien Vergez, Virginie Woisard, Benjamin Vairel, Jérôme Sarini, Ana Cavillon, Emilien Chabrillac   +7 more
wiley   +1 more source

Protein p16 as a marker of dysplastic and neoplastic alterations in cervical epithelial cells

BMC Cancer, 2004
Background Cervical carcinomas are second most frequent type of women cancer. Success in diagnostics of this disease is due to the use of Pap-test (cytological smear analysis).
Spitkovsky Dimitry, Bliev Alexander, Golovina Darya, Krutikova Ella, Frank Georgy, Andreeva Yulia, Zavalishina Larisa, Volgareva Galina, Ermilova Valeriya, Kisseljov Fjodor   +9 more
doaj   +1 more source

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili, Paolo Bossi, Luca Lalli, Lisa Francesca Linda Licitra, Marta Maddalo, Almalina Bacigalupo, Liliana Belgioia, Jon Cacicedo, Nadia Facchinetti, Almudena Garcia Castano, Marc Oliva, Pierluigi Bonomo, Giuseppe Sanguineti, Pierfrancesco Franco, Athanassios Argiris, Amanda Psyrri, Ester Orlandi   +16 more
wiley   +1 more source

Using formalin fixed paraffin embedded tissue to characterize the microbiota in p16-positive and p16-negative tongue squamous cell carcinoma: a pilot study

BMC Oral Health
Background Tongue squamous cell carcinoma (TSCC) is the most common oral cavity cancer, and p16 immunohistochemistry is an exact and available tool in the prognostic and predictive characterization of squamous cell cancers in the head and neck ...
Zhan Yuanbo, Liu Tianyi, Song Xuejing, Liu Xinpeng, Wang Jianqun, Xu Wenxia, Geng Jingshu   +6 more
doaj   +1 more source

Chemistry in Evaporating Ices: Unexplored Territory

, 2010
We suggest that three-body chemistry may occur in warm high density gas evaporating in transient co\textendash desorption events on interstellar ices. Using a highly idealised computational model we explore the chemical conversion from simple species of ...
Boogert, Cesare Cecchi-Pestellini, David A. Williams, Garrod, Gibb, Glasstone, Jonathan M. C. Rawlings, Serena Viti, Tielens, Tsuji, Whittet   +10 more
core   +1 more source

Disease Site‐Specific Outcomes in p16‐Positive Non‐Oropharyngeal Mucosal Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Objectives To report disease‐free survival (DFS) in p16‐positive non‐oropharyngeal head‐and‐neck squamous‐cell carcinoma (HNSCC). Methods Curatively‐treated non‐oropharyngeal HNSCC (2009–2021) were reviewed. DFS was compared among p16‐positive, p16‐negative, and p16‐untested cases for the overall cohort and by disease site.
Revadhi C. Chelvarajah, Lessandra Y. S. Chee, Jie Su, Brian O'Sullivan, Christopher M. K. L. Yao, Enrique Sanz‐Garcia, Stephen M. Smith, Ilan Weinreb, Scott Bratman, B. C. John Cho, Ezra Hahn, Andrew Hope, Ali Hosni, John Kim, Andrew McPartlin, Nauman Malik, Chiaojung Jillian Tsai, John de Almeida, Anna Spreafico, Li Tong, Shao Hui Huang, John N Waldron   +21 more
wiley   +1 more source

Impact of Smoking on Treatment Outcomes in Patients With Human Papillomavirus‐Related Oropharyngeal Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with HPV+ oropharyngeal cancer (OPC) have worse outcomes with longer smoking history (≥ 10 pack‐years). This has been confirmed in trials of primary radiotherapy but not surgery, suggesting differential smoking impact by treatment received. We assessed smoking‐related outcomes at a single institution.
Michelle M. Kwan, Latifa A. Bazzi, Zequn Sun, Dayton Rand, Asher Park, Shravan Asthana, Alexis Larson, Poonam Yadav, Bharat B. Mittal, Adil Akthar, Sarah Kramer, Jochen H. Lorch, Sandeep Samant, Urjeet Patel, Michelle L. Mierzwa, Leila J. Mady, Katelyn O. Stepan, Laila A. Gharzai   +17 more
wiley   +1 more source