Results 181 to 190 of about 217,248 (344)

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

P1PK blood group antigens in birds: implications for veterinary blood transfusion, human and pet health. [PDF]

BMC Vet Res
Bereznicka A, Duk M, Kapczynska K, Modlinska A, Piasecki T, Link-Lenczowski P, Heidorn-Czarna M, Pasikowski P, Czerwinski M, Kaczmarek R.   +9 more
europepmc   +1 more source

Referee report. For: Refractory hypotension during general anesthesia despite preoperative discontinuation of an angiotensin receptor blocker [v1; indexed, http://f1000r.es/p1]

, 2013
Sumio Hoka
openalex   +1 more source

Tyrosine Phosphorylation of the Human Glutathione S-Transferase P1 by Epidermal Growth Factor Receptor [PDF]

, 2009
Tatsunori Okamura, Simendra Singh, John K. Buolamwini, Timothy Haystead, Henry S. Friedman, Darell D. Bigner, Francis Ali‐Osman   +6 more
openalex   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Altered Network Function in Hippocampus After Sub-Chronic Activation of Cannabinoid Receptors in Early Adolescence. [PDF]

Int J Mol Sci
Rehn J, Admeus L, Kocsis B.
europepmc   +1 more source

P1‐398: SUVN‐D4010: NOVEL 5‐HT4 RECEPTOR PARTIAL AGONIST FOR THE TREATMENT OF ALZHEIMER'S DISEASE [PDF]

, 2014
Nageswararao Muddana, Ramkumar Subramanian, Medapati Rajesh Babu, Renny Abraham, Rama Lakshmana Karthik Gadi, Vijay Benade, Veera Raghava Chowdary Palacharla, Arunkumar Manoharan, Vinod Goyal, Santosh Kumar Pandey, Mohammed Abdul Rasheed, Srinivasa Rao Ravella, Ramakrishna Nirogi   +12 more
openalex   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

Purinergic Receptors in Dendritic Cells. [PDF]

J Inflamm Res
Wang M, Zhao X, Hou S, Wu Z, Yin HY.
europepmc   +1 more source

Machine Learning‐Enhanced Analysis of Exosomal Surface Sialic Acid Using Surface‐Enhanced Raman Spectroscopy for Ovarian Cancer Diagnosis and Therapeutic Monitoring

Advanced Science, EarlyView.
Machine learning‐assisted surface‐enhanced Raman spectroscopy analysis of exosomal sialic acid for ovarian cancer diagnosis, as well as independent monitoring of exosomal sialic acid expression levels across different treatment periods, reveals a potential correlation with treatment response.
Lili Cong, Jiaqi Wang, Sijun Huang, Xiaxia Man, Yi Guo, Shuping Xu, Songling Zhang   +6 more
wiley   +1 more source