Results 161 to 170 of about 1,469,677 (296)

Exercise as a modulator of purinergic signaling and inflammation in cancer-associated sarcopenia: a narrative review. [PDF]

Inflamm Res
de Oliveira EM, Dockhorn VMG, de Souza JVG, Franscescon F, de Resende E Silva DT.   +4 more
europepmc   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Modeling of the Glutamatergic Synaptic Transmission and its Modulation by Adenosine and Caffeine. [PDF]

Synapse
Britch M.
europepmc   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

Base editing reversal of radiation sensitivity in NHEJ1 immunodeficiency. [PDF]

J Hum Immun
Kadirkamanathan R, Preece R, Woodbine L, Korneeva E, Lazareva A, Ip W, Qasim W.   +6 more
europepmc   +1 more source

Physics Informed Generative Surrogate Learning for Full Wave Validated Real Time Beamforming in Programmable Metasurfaces

Advanced Electronic Materials, EarlyView.
A physics‐guided generative surrogate framework is developed for programmable metasurface beamforming. Mode‐conditioned binary state generation, aperture‐physics prediction, routed residual correction, NSGA‐II optimization, and CST validation are combined to support fast candidate screening and full‐wave beam refinement across single‐beam, dual‐beam ...
Wenqian Liu, Weidong Chen, Chang Chen, Xiang Zhang, Sensong An   +4 more
wiley   +1 more source

<i>NTRK</i>-positive collision tumor of the gastrointestinal tract: a rare entity case report. [PDF]

Ann Med Surg (Lond)
Sirek A, Amann VC, Uzun S, Bubendorf L, Rosenberg R, Burri E, Häuptle P, Roma L, Mertz KD.   +8 more
europepmc   +1 more source

Alcohol‐Adduct Mediated Precursor Stabilization Strategies for Conformal SnO2 Layers in Highly Efficient and Stable Perovskite Solar Modules

Advanced Energy Materials, EarlyView.
An alcohol‐adduct‐mediated strategy is employed to stabilize tin isopropoxide for the formation of a homogeneous double electron transport layer (ETL) incorporating SnO2 nanoparticles (NPs). This double‐ETL exhibits improved optical and charge‐transport properties due to reduced defect density and better energy level alignment, resulting in high ...
You‐Hyun Seo, Eun Young Park, Chan Su Moon, Dong Gyu Lee, Junho Park, Fabian Rotermund, Gill Sang Han, Tae Kyung Lee, Nam Joong Jeon, Bong Joo Kang, Young Yun Kim   +10 more
wiley   +1 more source

Analysis of in vitro profiling data of cosmetic ingredients within the Tox21 10K compound library for bioactivity and potential toxicity. [PDF]

BMC Pharmacol Toxicol
Kruger L, Ngan DK, Xu T, Xia M, Ferguson SS, Reif DM, Simeonov A, Huang R.   +7 more
europepmc   +1 more source

Artificial Intelligence–Based Surgical Phase Analysis Enables Objective Assessment of Surgeon Skill in Robotic Distal Gastrectomy: A Multicenter Study

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Artificial intelligence (AI)–based surgical video analysis can automate time‐consuming manual assessments and enable objective characterization of surgical workflows. We aimed to construct a large, multicenter, fully annotated dataset of robotic distal gastrectomy (RDG) videos and evaluate the feasibility and performance of an AI model for
Masaru Komatsu, Daichi Kitaguchi, Yoichi Ninomiya, Yuya Takabe, Mitsumasa Yoshida, Masahiro Yura, Nobuyoshi Takeshita, Takahiro Kinoshita, Masaaki Ito   +8 more
wiley   +1 more source