Results 71 to 80 of about 1,469,677 (296)

Scavenger receptor CL-P1 mediates endocytosis by associating with AP-2μ2

Biochimica et Biophysica Acta (BBA) - General Subjects, 2014
Scavenger receptor CL-P1 (collectin placenta 1) has been found recently as a first membrane-type collectin which is mainly expressed in vascular endothelial cells. CL-P1 can endocytose OxLDL as well as microbes but in general, the endocytosis mechanism of a scavenger receptor is not well elucidated.We screened a placental cDNA library using a yeast two-
SeongJae, Jang, Ohtani, Katsuki, Fukuoh, Atsushi, Mori, Kenichiro, Yoshizaki, Takayuki, Kitamoto, Noritoshi, YounUck, Kim, Suzuki, Yasuhiko, Wakamiya, Nobutaka   +8 more
openaire   +4 more sources

Bio‐Inspired Object Retrieval via Proximity‐Guided Adaptive Thigmotactic Exploration and Neuromorphic Recognition

Advanced Robotics Research, EarlyView.
Sparse active‐infrared proximity sensing is coupled to an adaptive thigmotactic controller for camera‐inaccessible object retrieval. After grasping, receptor‐informed encoding transforms force, temperature, and wrist force–torque signals into spike trains for spiking neural network recognition.
Fengyi Wang, Nitish Thakor, Gordon Cheng
wiley   +1 more source

Localization of CGRP and VEGF mRNAs in the mouse superior cervical ganglion during pre- and postnatal development

European Journal of Histochemistry, 2018
The neuropeptide calcitonin gene-related peptide (CGRP) mediates inflammation and head pain by influencing the functional vascular blood supply. CGRP is a well-characterized mediator of receptor-regulated neurotransmitter release.
Kazuyuki Mitsuoka, Yoko Miwa, Takeshi Kikutani, Iwao Sato   +3 more
doaj   +1 more source

Effect of bacteriophage P1 lysogeny on lipopolysaccharide composition and the lambda receptor of Escherichia coli [PDF]

Journal of Bacteriology, 1984
The outer membrane of Escherichia coli was altered as a consequence of lysogeny by bacteriophages P1 and P1 cmts. The predominant change was a reduction in the size of lipopolysaccharide to a heptose-deficient form. P1 cmts lysogens were still sensitive to several bacteriophages but were resistant to lambda vir.
J M, Tomás, W W, Kay
openaire   +2 more sources

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Blue Mussel-Derived Bioactive Peptides PIISVYWK (P1) and FSVVPSPK (P2): Promising Agents for Inhibiting Foam Cell Formation and Inflammation in Cardiovascular Diseases

Marine Drugs
Atherosclerosis is a key etiological event in the development of cardiovascular diseases (CVDs), strongly linked to the formation of foam cells. This study explored the effects of two blue mussel-derived bioactive peptides (BAPs), PIISVYWK (P1) and ...
Chathuri Kaushalya Marasinghe, Jae-Young Je   +1 more
doaj   +1 more source

Phosphorylation of DCC by ERK2 Is Facilitated by Direct Docking of the Receptor P1 Domain to the Kinase [PDF]

, 2010
SummaryNetrin receptor DCC plays critical roles in many cellular processes, including axonal outgrowth and migration, angiogenesis, and apoptosis, but the molecular basis of DCC-mediated signaling is largely unclear. ERK2, a member of the MAPK family, is
Mingjie Zhang, Wen, Wenyu, Yuan Shang, Wenfu Ma, Wang, Wenning, Wenning Wang, Ma, Wenfu, Zhang, Mingjie, Wenyu Wen, Shang, Yuan, Wei, Zhiyi, Zhiyi Wei   +11 more
core   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

Advanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang, Jiayi Xu, Liang Ran, Xinhe Feng, Khalil Harrabi, Yida Li, Longyang Lin, Feichi Zhou   +7 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Mapping putative allosteric sites in rhodopsin and elucidating the structural basis of retigabine modulation

Journal of Photochemistry and Photobiology
Rhodopsin (Rho), a prototypical G protein–coupled receptor (GPCR) is the sensory receptor essential for dim-light vision. Its misfolding is a major cause of retinitis pigmentosa (RP), a group of inherited retinal degenerative diseases.
Jenifar Das, Melvin Nadir Rosalez, Patricia Gomez-Gutierrez, Feifei Wang, Nora Puig-Puig, Alejandro Cruz, Marlet Martinez-Archundia, Pere Garriga, Juan J. Perez   +8 more
doaj   +1 more source