Results 101 to 110 of about 481,863 (320)

Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line

Journal of Biomedical Science, 2012
Background Studies have shown the existence of p21 induction in a p53-dependent and -independent pathway. Our previous study indicates that DOX-induced p65 is able to bind the p21 promoter to activate its transactivation in the cells.
Zhou YingQi, Li Gang, Ji Yuan, Liu Chen, Zhu JingPing, Lu YanJun   +5 more
doaj   +1 more source

Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest [PDF]

, 2015
TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Bellamy, Christopher O, Dunbar, Donald R, Harrison, David J, Prost, Sandrine, Sheahan, Sharon   +4 more
core   +1 more source

Pentagonal 2D Altermagnets: Material Screening and Altermagnetic Tunneling Junction Device Application

Advanced Functional Materials, EarlyView.
From a database of 170 pentagonal 2D materials, 4 candidates exhibiting altermagnetic ordering are screened. Furthermore, the spin‐splitting and unconventional boundary states in the pentagonal 2D altermagnetic monolayer MnS2 are investigated. A MnS2‐based altermagnetic tunneling junction is designed and, through ab initio quantum transport simulations,
Jianhua Wang, Xingyue Yang, Zongmeng Yang, Jing Lu, Pin Ho, Wenhong Wang, Yee Sin Ang, Zhenxiang Cheng, Shibo Fang   +8 more
wiley   +1 more source

Long-term prognostic value of the combination of EORTC risk group calculator and molecular markers in non-muscle-invasive bladder cancer patients treated with intravesical Bacille Calmette-Guérin

Urology Annals, 2011
Background and Objectives: To evaluate the long-term prognostic value of the combination of the EORTC risk calculator and proapoptotic, antiapoptotic, proliferation, and invasiveness molecular markers in predicting the outcome of intermediate- and high ...
Sultan S Alkhateeb, Mischel Neill, Sas Bar-Moshe, Bas Van Rhijn, David M Kakiashvili, Neil Fleshner, Michael Jewett, Michel Petein, Claude Schulman, Sally Hanna, Peter J Bostrom, Thierry Roumeguere, Shahrokh F Shariat, Sandrine Rorive, Alexandre R Zlotta   +14 more
doaj   +1 more source

Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non–small cell lung cancer cell proliferation by epigenetically repressing p21 expression

Molecular Cancer, 2018
Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a pivotal role in cancer biology. However, the role and molecular mechanism and global genes that were mediated by lncRNA AFAP1-AS1 in non–small cell lung cancer (NSCLC) remain ...
D. Yin, Xiyi Lu, Jun Su, Xuezhi He, W. De, Jin-song Yang, Wei Li, Liang Han, E. Zhang   +8 more
semanticscholar   +1 more source

Stability of AdSp×Mq compactifications without supersymmetry [PDF]

, 2001
We study the stability of Freund-Rubin compactifications, AdSp×Mq, of (p+q)-dimensional gravity theories with a q-form field strength and no cosmological term.
DeWolfe, Oliver, Freedman, Daniel Z., Gubser, Steven S., Horowitz, Gary T., Mitra, Indrajit   +4 more
core   +2 more sources

Synergistic Compatibilization of CsPbBr3 Perovskites and HfO2 Nanocrystals for Hybrid Sensitized Nanoscintillators

Advanced Functional Materials, EarlyView.
Lead halide perovskite nanocrystals are promising scintillators but suffer from reabsorption losses and limited compatibility with high‐Z additives. Hybridization of CsPbBr3 nanocrystals with PbBr2‐passivated HfO2 nanoparticle sensitizers, achieved during or after synthesis, produces stable composites with maintained optical quality, improved ...
Francesco Bruni, Saptarshi Chakraborty, Andrea Fratelli, Abdessamad El Adel, Jordi Llusar, Francesco Carulli, Matteo L. Zaffalon, Chenger Wang, Vojtech Zabloudil, Etiennette Auffray, Francesco Meinardi, Leonardo Poletti, Laura Lazzarini, Daniela Manno, Anna Galli, Francesca Rossi, Ivan Infante, Sergio Brovelli   +17 more
wiley   +1 more source

Expression of p53, Ki67, epidermal growth factor receptor, transforming growth-factorα, and p21 in primary and secondary hyperparathyroidism

Indian Journal of Endocrinology and Metabolism, 2014
Background: Secondary hyperparathyroidism (SH) is major problem in chronic renal failure. There are studies to examine proliferation and apoptosis associated biomarkers expressions in parathyroid lesions to reveal specific features.
Saime Paydas, Arbil Acikalim, Bulent Kaya, Bermal Hasbay Bicer, Mehmet Ulker, Orhan Demircan, Aysun Uguz, Mustafa Balal, Gurhan Sakman, Yasar Sertdemir, Refika Karaer, Eda Altun   +11 more
doaj   +1 more source

Does a Morphotropic Phase Boundary Exist in ZrxHf1‐xO2‐Based Thin Films?

Advanced Functional Materials, EarlyView.
This study investigates 6 nm zirconium‐rich hafnium‐zirconium oxide thin–film metal–insulator–metal capacitors using a combination of experimental methods and machine learning–based molecular dynamics simulations to provide insight into the physical mechanisms that enhance the dielectric constant near 0 V and attribute it to the field‐induced ...
Pramoda Vishnumurthy, Richard Ganser, Dong‐Gyu Kim, Intak Jeon, Chang Hwa Jung, Hanjin Lim, Thomas Mikolajick, Susan Trolier‐McKinstry, Alfred Kersch, Uwe Schroeder   +9 more
wiley   +1 more source

MicroRNA-203 Regulates Growth and Metastasis of Breast Cancer

Cellular Physiology and Biochemistry, 2015
Backgrounds/Aims: MicroRNAs (MiRNAs) control many biological events and play critical roles in the development of tumor. Among all miRNAs, miR203 has been recently shown to have an inhibitory effect on prostate cancer.
Shan Zhao, Jinzhu Han, Likang Zheng, Zixin Yang, Li Zhao, Yingqian Lv   +5 more
doaj   +1 more source