Results 181 to 190 of about 135,146 (307)

P2Y12 receptor gene mutations associated with bleeding

Platelets, 2017
Mariangela Scavone, Eti A. Femia, Marco Cattaneo   +2 more
doaj   +1 more source

Purine and Pyrimidine (P2) Receptors as Drug Targets

, 2002
Kenneth A. Jacobson, Michael F. Jarvis, Michael Williams   +2 more
openalex   +2 more sources

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

Advanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong, Ziyun Liang, Tianqi Duo, Liping Pan, Qi Zhu, Jiete Liang, Xianyao Luo, Qingcai Feng, Rong Xu, Yihao Liu, Xu Chen, Luxi Chen, Xiaohong Liu, Yaosheng Chen, Delin Mo   +14 more
wiley   +1 more source

P2 Receptors Influence hMSCs Differentiation towards Endothelial Cell and Smooth Muscle Cell Lineages. [PDF]

Int J Mol Sci, 2020
Zhang Y, Babczyk P, Pansky A, Kassack MU, Tobiasch E.   +4 more
europepmc   +1 more source

The German Research Unit “Neuronal and glial P2 receptors; molecular basis and functional significance” [PDF]

, 2010
Torsten Schöneberg, Péter Illés, Geoffrey Burnstock   +2 more
openalex   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes

Advanced Science, EarlyView.
Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis, Chiara Lazzarini, Rahmetullah Durgun, Barbara Barile, Giorgia Conte, Tamara Posati, Marco Caprini, Grazia Paola Nicchia, Valentina Benfenati, Michelle Y. Sander   +9 more
wiley   +1 more source

P2 Receptor Antagonists Rescue Defective Heme Content in an In Vitro SLC25A38-Associated Congenital Sideroblastic Anemia Cell Model [PDF]

Antonella Santoro, Silvia De Santis, Ferdinando Palmieri, Angelo Vozza, Gennaro Agrimi, Immacolata Andolfo, Roberta Russo, Antonio J. Palazzo, Clelia Tiziana Storlazzi, Arianna Ferrucci, Yong Woong Jun, Eric T. Kool, Giuseppe Fiermonte, Achille Iolascon, Eleonora Paradies, C Marobbio, Luigi Palmieri   +16 more
openalex   +1 more source

Photo‐Empowered Macrophage‐Based Drug Delivery System Overcomes Motility Suppression and Significantly Enhances Deep Tumor Drug Delivery

Advanced Science, EarlyView.
This study develops a photo‐empowered macrophage‐based (PEM) drug delivery system that provides a novel and effective solution for restoring cellular motility to enhance drug delivery and overcome hypoxia‐induced multidrug resistance. The construction of the PEM system fully exploits the unique biological properties of macrophages and the energy ...
Zhaoming Fu, Xin Cui, Shanshan Liu, Lu Gao, Yingang Sun, Yujun Chen, Mianlong Li, Yuxin Fan, Jing Kuang, Wen Song, Feifan Zhou   +10 more
wiley   +1 more source

Suramin and reactive blue 2, P2-purinoceptor antagonists, block GABA and glutamate receptor channels in rat hippocampal neurons

, 1995
Kazuhide Inoue, Ken Nakazawa, Kaori Inoue, Kanako Ito, Schuichi Koizumi   +4 more
openalex   +1 more source