Results 261 to 270 of about 130,183 (288)
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1998
Extracellular purines and pyrimidines regulate blood flow by important effects on vascular tone mediated via cell surface P2 receptors. P2 receptors are divided into two superfamilies, P2X and P2Y, according to whether they are ligand-gated cation channels or are coupled to G proteins respectively.
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Extracellular purines and pyrimidines regulate blood flow by important effects on vascular tone mediated via cell surface P2 receptors. P2 receptors are divided into two superfamilies, P2X and P2Y, according to whether they are ligand-gated cation channels or are coupled to G proteins respectively.
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P2 receptors, platelet function and pharmacological implications
Thrombosis and Haemostasis, 2008SummaryADP and ATP play a crucial role in platelet activation and their receptors are potential targets for antithrombotic drugs. The ATP-gated cation channel P2X1 and the two G protein-coupled ADP receptors, P2Y1 and P2Y12, selectively contribute to platelet aggregation and formation of a thrombus.Owing to its central role in the growth and ...
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Transcriptional control of energy metabolism by nuclear receptors
Nature Reviews Molecular Cell Biology, 2022Charlotte Scholtes, Vincent Giguère
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Mutual potentiation of plant immunity by cell-surface and intracellular receptors
Nature, 2021Bruno Pok Man Ngou +2 more
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Teaching old receptors new tricks: biasing seven-transmembrane receptors
Nature Reviews Drug Discovery, 2010Sudarshan Rajagopal +2 more
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REV-ERB and ROR nuclear receptors as drug targets
Nature Reviews Drug Discovery, 2014Douglas J Kojetin, Thomas P Burris
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Therapeutic potential of ectopic olfactory and taste receptors
Nature Reviews Drug Discovery, 2018Sung-Joon Lee +2 more
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Targeting proteinase-activated receptors: therapeutic potential and challenges
Nature Reviews Drug Discovery, 2012Rithwik Ramachandran +2 more
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