Results 41 to 50 of about 39,255 (248)

Evolution of P2X receptors [PDF]

open access: yesWiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2012
AbstractPurines appear to be the most primitive and widespread chemical messengers in all kingdoms of the Domain Eucarya. There is evidence for purinergic signaling in plants, invertebrates, and lower vertebrates from protozoa to birds. Much is based on pharmacological studies, but important recent papers have utilized the techniques of molecular ...
Alexei Verkhratsky, Geoffrey Burnstock
openaire   +2 more sources

Conserved Extracellular Cysteines Differentially Regulate the Potentiation Produced by Zn2+ in Rat P2X4 Receptors [PDF]

open access: yes, 2013
One feature of the amino acid sequence of P2X receptors identified from mammalian species, Xenopus laevis and zebrafish is the conservation of ten cysteines in the extracellular loop.
Chen, Lin   +7 more
core   +2 more sources

Pathophysiological Role of Purinergic P2X Receptors in Digestive System Diseases

open access: yesFrontiers in Physiology, 2021
P2X receptors (P2XRs) are trimeric, non-selective cation channels activated by extracellular ATP and widely distributed in the digestive system. P2XRs have an important role in the physiological function of the digestive system, such as neurotransmission,
Qimin An   +23 more
doaj   +1 more source

The BCS Critical Temperature in a Weak External Electric Field via a Linear Two-Body Operator [PDF]

open access: yes, 2018
We study the critical temperature of a superconductive material in a weak external electric potential via a linear approximation of the BCS functional. We reproduce a similar result as in Frank et al.
C Hainzl   +11 more
core   +1 more source

Post-translational regulation of P2X receptor channels: modulation by phospholipids

open access: yesFrontiers in Cellular Neuroscience, 2013
P2X receptor channels mediate fast excitatory signaling by ATP and play major roles in sensory transduction, neuro-immune communication and inflammatory response.
Louis-Philippe eBernier   +2 more
doaj   +1 more source

The Necessity of Dynamic Workflow Managers for Advancing Self‐Driving Labs and Optimizers

open access: yesAdvanced Intelligent Discovery, EarlyView.
We assess the maturity and integration readiness of key methodologies for Materials Acceleration Platforms, highlighting the need for dynamic workflow managers. Demonstrating this, we integrate PerQueue into a color‐mixing robot, showing how flexible orchestration improves coordination and optimization.
Simon K. Steensen   +6 more
wiley   +1 more source

P2X₃ Knock-Out Mice Reveal a Major Sensory Role for Urothelially Released ATP [PDF]

open access: yes, 2001
The present study explores the possible involvement of a purinergic mechanism in mechanosensory transduction in the bladder using P2X₃ receptor knock-out (P2X₃ ⁻⁄⁻) and wild-type control (P2X₃ ⁺⁄⁺) mice.
Bardini, M   +7 more
core  

Parasupersymmetric Quantum Mechanics with Generalized Deformed Parafermions [PDF]

open access: yes, 1996
A superposition of bosons and generalized deformed parafermions corresponding to an arbitrary paraquantization order $p$ is considered to provide deformations of parasupersymmetric quantum mechanics.
Beckers, J., Debergh, N., Quesne, C.
core   +3 more sources

Genetics of Response to ECT, TMS, Ketamine and Esketamine

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Treatment‐resistant mood disorders are often managed with intensive interventions that include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine, and esketamine, but the role of genetics in clinical response to those interventions is yet to be clearly determined.
Clio E. Franklin   +18 more
wiley   +1 more source

Subunit Arrangement in P2X Receptors [PDF]

open access: yesThe Journal of Neuroscience, 2003
ATP-gated ionotropic receptors (P2X receptors) are distributed widely in the nervous system. For example, a hetero-oligomeric receptor containing both P2X2and P2X3subunits is involved in primary afferent sensation. Each subunit has two membrane-spanning domains.
Jiang, Lin Hua   +5 more
openaire   +3 more sources

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