Results 91 to 100 of about 689,514 (206)

Enteric Neurons and Glial Cells Are Partially Protected in P2X7 Receptor‐Deficient Mice With Ulcerative Colitis

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 11, November 2026.
P2X7R knockout mice efficacy. Chronic DSS‐induced colitis decreased the nitrergic and cholinergic neurons, β3‐tubulin–ir neurons, and GFAP‐ir and S100β glial cells in WT/DSS and KO/DSS groups. P2X7R‐ir cells decreased in WT/DSS animals, and NLRP3‐ir cells increased mostly in WT/DSS, indicating inflammasome activation.
Roberta Figueiroa Souza   +3 more
wiley   +1 more source

The P2X receptor mediated regulation of inhibitory synaptic transmission [PDF]

open access: yes
In the central nervous system ATP can be released by neurons and glial cells through similar pathways as other neurotransmitters. Extracellular ATP targets P2X purinoreceptors, causing an influx of Ca2+ ions which transmit very important messages for ...
Andrew-Adiamah, Jemma
core  

Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity

open access: yesMolecular Pain, 2010
Background To evaluate whether P2X receptors are involved in responses to noxious pulp stimulation, the P2X3 and P2X2/3 receptor agonist α,β-methyleneATP (α,β-meATP) was applied to the molar tooth pulp and nocifensive behavior and extracellular-signal ...
Sessle Barry J   +10 more
doaj   +1 more source

Supporting AI Readiness Through Digital Workflows in Materials Science

open access: yesAdvanced Engineering Materials, Volume 28, Issue 20, 21 October 2026.
Digitalization drives innovation in materials science by connecting data silos and turning heterogeneous processes into reusable research pipelines. Across 13 MaterialDigital projects, digital workflows reveal complementary pathways toward AI‐ready materials research, founded on structured data, persistent artifacts, executable orchestration, and ...
Marian Bruns   +67 more
wiley   +1 more source

Functional distribution of Ca2+-coupled P2 purinergic receptors among adrenergic and noradrenergic bovine adrenal chromaffin cells

open access: yesBMC Neuroscience, 2007
Background Adrenal chromaffin cells mediate acute responses to stress through the release of epinephrine. Chromaffin cell function is regulated by several receptors, present both in adrenergic (AD) and noradrenergic (NA) cells.
Castro Enrique   +3 more
doaj   +1 more source

Point Mutation in the Mouse P2X Receptor Affects Intercellular Calcium Waves in Astrocytes

open access: yesASN Neuro, 2009
Purinergic P2 receptors and gap junctions are two groups of proteins involved in the transmission of ICWs (intercellular calcium waves) between astrocytes.
Sylvia O Suadicani   +3 more
doaj   +1 more source

P2X receptors in sensory neurones

open access: yesBritish Journal of Anaesthesia, 2000
P2X receptors are a family of ligand-gated ion channels responsive to ATP. Seven subtypes have been identified which form homo-multimeric or hetero-multimeric pores. P2X3 receptors are selectively expressed predominantly on small-diameter nociceptive sensory neurones in the dorsal root, trigeminal and nodose ganglia, particularly the non-peptidergic ...
openaire   +2 more sources

Characterisation of canine P2X and P2Y receptors

open access: yes, 2021
Purinergic signalling is an important biological process that utilises extracellular nucleotides to activate P2X and P2Y purinergic receptors. P2 receptors play a range of roles in human physiology and pathophysiology. Despite this, little is known about
Reece Andrew Sophocleous (20166279)
core   +1 more source

P2X1 receptors and the endothelium

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
Adenosine triphosphate (ATP) is now established as a principle vaso-active mediator in the vasculature. Its actions on arteries are complex, and are mediated by the P2X and P2Y receptor families.
LS Harrington, JA Mitchell
doaj   +1 more source

Comparative Embryonic Spatio-Temporal Expression Profile Map of the Xenopus P2X Receptor Family

open access: yesFrontiers in Cellular Neuroscience, 2019
P2X receptors are ATP-gated cations channels formed by the homo or hetero-trimeric association from the seven cloned subunits (P2X1-7). P2X receptors are widely distributed in different organs and cell types throughout the body including the nervous ...
Camille Blanchard   +5 more
doaj   +1 more source

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