Results 61 to 70 of about 11,033 (176)
Ecology and Evolution, Volume 16, Issue 3, March 2026.We present the first high‐quality annotated genome of Pinna rudis and an updated genome assembly for Pinna nobilis, two Mediterranean fan mussel species differentially affected by mass mortality events. Comparative genomic analyses of gene sets associated with the “defensome” show that these genes are largely functionally conserved between the two ...
Stéphane Coupé +6 more
wiley +1 more source
A shared mechanism for TNP-ATP recognition by members of the P2X receptor family
Computational and Structural Biotechnology JournalP2X receptors (P2X1–7) are non-selective cation channels involved in many physiological activities such as synaptic transmission, immunological modulation, and cardiovascular function.
Xiao-Bo Ma +11 more
doaj +1 more source
Spatio‐Temporal Diversity of Calcium Activity in Microglia
Glia, Volume 74, Issue 3, March 2026.Ca2+ activity mostly occurs in microglial processes and stays localized. When it spreads, it often shows a directional bias and is constrained by branch points. Activity strongly relies on P2Y12 receptors and is shaped by neuronal activity. ABSTRACT Microglia, the brain's innate immune cells, possess complex, highly motile branched processes. These act
Hiroshi Horiuchi +3 more
wiley +1 more source
P2X receptors as targets for the treatment of status epilepticus
Frontiers in Cellular Neuroscience, 2013 Prolonged seizures are amongst the most common neurological emergencies. Status epilepticus is a state of continuous seizures that is life-threatening and prompt termination of status epilepticus is critical to protect the brain from permanent damage ...
David C Henshall +7 more
doaj +1 more source
Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.ABSTRACT Background Zika virus (ZIKV) is a flavivirus that has gained global attention due to its association with congenital microcephaly and neuroinflammatory responses. Markers of endothelial activation and purinergic signaling have been identified in the context of ZIKV neuropathogenesis, although the underlying mechanisms remain poorly understood.
Jorge Rodrigues de Sousa +12 more
wiley +1 more source
Molecular Pain, 2010 Background To evaluate whether P2X receptors are involved in responses to noxious pulp stimulation, the P2X3 and P2X2/3 receptor agonist α,β-methyleneATP (α,β-meATP) was applied to the molar tooth pulp and nocifensive behavior and extracellular-signal ...
Sessle Barry J +10 more
doaj +1 more source
P2X receptors and acupuncture analgesia
Brain Research Bulletin, 2019 Purinergic signaling has recently been suggested to constitute the cellular mechanism underlying acupuncture-induced analgesia (AA). By extending the original hypothesis on endogenous opioids being released during AA, Geoffrey Burnstock and Maiken Nedergaard supplied evidence for the involvement of purinoceptors (P2 and P1/A1 receptors) in the ...
Yong Tang +4 more
openaire +2 more sources
Journal of Flood Risk Management, Volume 19, Issue 1, March 2026.ABSTRACT Flood loss mapping is one of the essential prerequisites for urban flood assessment studies to identify areas vulnerable to floods and to make cities safe and resilient. This study develops a neuro‐fuzzy loss model to generate flood loss maps, classifying loss levels into several categories ranging from no loss to severe loss.
Mahdi Sedighkia +2 more
wiley +1 more source
Point Mutation in the Mouse P2X Receptor Affects Intercellular Calcium Waves in Astrocytes
ASN Neuro, 2009 Purinergic P2 receptors and gap junctions are two groups of proteins involved in the transmission of ICWs (intercellular calcium waves) between astrocytes.
Sylvia O Suadicani +3 more
doaj +1 more source