Results 31 to 40 of about 25,852 (233)
The future of P2Y12 receptor antagonists [PDF]
, 2015 Platelet P2Y12 inhibitors have become a central component of the treatment strategy for patients with atherothrombosis due to the importance of platelet P2Y12 receptors in arterial thrombosis.
Thomas, Mark R; id_orcid +1 more
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Perioperative P2Y12 Platelet Function Testing [PDF]
, 2021 Purpose: The purpose of this article is to review the need for platelet function P2Y12 testing in the perioperative vascular setting to identify the possibility of clopidogrel resistance (CR), and thus allow for alternative antiplatelet prescribing ...
Roberts, David
core
P2Y12 Inhibitor Monotherapy after Percutaneous Coronary Intervention [PDF]
, 2022 In patients with acute and chronic coronary artery disease undergoing percutaneous coronary intervention (PCI), dual antiplatelet therapy (DAPT) has been the cornerstone of pharmacotherapy for the past two decades.
Dominick J. Angiolillo +5 more
core +1 more source
Vascular Health and Risk Management, 2023 Rakhmad Hidayat,1– 3 Al Rasyid,2,3 Salim Harris,2,3 Alida Harahap,2 Herqutanto,2 Melva Louisa,2 Erlin Listiyaningsih,4 Aldy Safruddin Rambe,5 Tonny Loho6 1Doctoral Program in Medical Sciences Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia;
Hidayat R +8 more
doaj
Antinociceptive Effect of Magnolol in a Neuropathic Pain Model of Mouse
Journal of Pain Research, 2021 Xiao Zhang,1,* Juntao Wang,1,* Aihua Sui,2 Nannan Zhang,1 Qiulan Lv,2 Zhenfang Liu3 1Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, 266000, People’s Republic of China; 2Medical Research Center, The ...
Zhang X +5 more
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Polimorfisme P2Y12 Terhadap Agregasi Platelet Pada Pasien Penyakit Jantung Koroner [PDF]
, 2019 Genetic polymorphism of P2Y12 receptor is one of the factors responsible for the variation in response to antiplatelet therapy. Variations in response to P2Y12 receptors can cause Coronary Artheri Disease (CAD) in CHD patients.
hermawatiningsih, oktaviarika dewi
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Genotype-Guided Use of P2Y12 Inhibitors: A Review of Current State of the Art
Frontiers in Cardiovascular Medicine, 2022 The pharmacodynamics of the purinergic receptor type Y, subtype 12 (P2Y12) inhibitors has evolved. Our understanding of the metabolism of P2Y12 inhibitors has revealed polymorphisms that impact drug metabolism and antiplatelet efficacy, leading to ...
Abdullah Al-abcha +6 more
doaj +1 more source
Platelets, 2022 Platelet activation by adenosine diphosphate (ADP) is mediated through two G-protein-coupled receptors, P2Y1 and P2Y12, which signal through Gq and Gi, respectively.
Carol Dangelmaier, Satya P Kunapuli
doaj +1 more source
Loss of P2Y12 Has Behavioral Effects in the Adult Mouse [PDF]
, 2021 While microglia have been established as critical mediators of synaptic plasticity, the molecular signals underlying this process are still being uncovered.
Ania K. Majewska +6 more
core +1 more source
Platelets, 2018 The release of ADP from platelet dense granules and its binding to platelet P2Y12 receptors is key to amplifying the initial hemostatic response and propagating thrombus formation.
Annachiara Mitrugno +7 more
doaj +1 more source