Results 51 to 60 of about 27,659 (185)

P2Y12 Inhibitor Monotherapy or Dual Antiplatelet Therapy After Complex Percutaneous Coronary Interventions. [PDF]

, 2023
BACKGROUND It remains unclear whether P2Y12 inhibitor monotherapy preserves ischemic protection while limiting bleeding risk compared with dual antiplatelet therapy (DAPT) after complex percutaneous coronary intervention (PCI).
Watanabe, Hirotoshi, Gragnano, Felice, Song, Young Bin, Vranckx, Pascal, Angiolillo, Dominick J., Zhao, Qiang, Hong, Sung-Jin, Dangas, George D, Gibson, Charles M, Gwon, Hyeon-Cheol, Hahn, Joo-Yong, Calabro', Paolo, McFadden, Eugene P., Ando, Kenji, Calabrò, Paolo, Angiolillo, Dominick J, McFadden, Eùgene P, Kim, Byeong-Keuk, Heg, Dik, Windecker, Stephan, Branca, Mattia, Bin Song, Young, Zhu, Yunpeng, Gibson, Charles M., Baber, Usman, Dangas, George D., Franzone, Anna, Jang, Yangsoo, Kimura, Takeshi, Mehta, Shamir, Serruys, Patrick W., Mehran, Roxana, Serruys, Patrick W, Valgimigli, Marco   +33 more
core   +1 more source

Evaluation of Treatment Response of Calcified Nodules and Nodular Calcified Lesions Using Mean Density on Coronary Computed Tomography Angiography

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Calcified nodules (CN) and nodular calcifications (NC) present significant challenges during percutaneous coronary intervention (PCI) because of their protruding morphology and high rigidity, which often result in inadequate stent expansion and suboptimal procedural outcomes.
Akito Setoguchi, Keita Iyama, Ryosuke Iwasaki, Saburo Kusumoto, Yoshiyuki Doi, Tatsuya Nunohiro, Masayoshi Takeno, Koji Maemura   +7 more
wiley   +1 more source

P2Y12 expression and function in alternatively activated human microglia [PDF]

, 2015
Objective: To investigate and measure the functional significance of altered P2Y12 expression in the context of human microglia activation. Methods: We performed in vitro and in situ experiments to measure how P2Y12 expression can influence disease ...
Moore, Craig S., Butovsky, Oleg, Rao, Vijayaraghava T.S., Bar-Or, Amit, Kinsara, Angham, Michell-Robinson, Mackenzie, Leong, Soo Yuen, Ludwin, Samuel K., Séguéla, Philippe, Ase, Ariel R., Antel, Jack P.   +10 more
core   +2 more sources

P2Y12 Inhibitor Monotherapy after Percutaneous Coronary Intervention

, 2022
In patients with acute and chronic coronary artery disease undergoing percutaneous coronary intervention (PCI), dual antiplatelet therapy (DAPT) has been the cornerstone of pharmacotherapy for the past two decades.
Dominick J. Angiolillo, Angiolillo, Dominick J., Xuan Zhou, Luis Ortega-Paz, Ortega-Paz, Luis, Zhou, Xuan   +5 more
core   +1 more source

Interaction of Operator−Patient Sex on Peri‐Procedural Treatments and Major Coronary Outcomes After Percutaneous Coronary Intervention

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background There are limited data evaluating the association between operator−patient sex, and outcomes in patients undergoing percutaneous coronary intervention (PCI). Methods We included 138,112 consecutive PCI procedures in patients presenting with acute coronary syndrome (ACS) in England and Wales, 2017−2020.
Sharon A. Ayayo, Vicky P. Taxiarchi, Angela Jerath, Evangelos Kontopantelis, Sonya N. Burgess, Sarah Zaman, Mamas A. Mamas   +6 more
wiley   +1 more source

Baicalin Depresses the Sympathoexcitatory Reflex Induced by Myocardial Ischemia via the Dorsal Root Ganglia

Frontiers in Physiology, 2018
Myocardial ischemia (MI) is one of the major causes of death in cardiac diseases. Purinergic signaling is involved in bidirectional neuronal-glial communication in the primary sensory ganglia.
Lifang Zou, Lifang Zou, Xinyao Han, Shuangmei Liu, Shuangmei Liu, Yingxin Gong, Bing Wu, Bing Wu, Zhihua Yi, Zhihua Yi, Hui Liu, Hui Liu, Shanhong Zhao, Shanhong Zhao, Tianyu Jia, Tianyu Jia, Lin Li, Lin Li, Huilong Yuan, Huilong Yuan, Liran Shi, Liran Shi, Chunping Zhang, Chunping Zhang, Yun Gao, Yun Gao, Guilin Li, Guilin Li, Hong Xu, Hong Xu, Shangdong Liang, Shangdong Liang   +31 more
doaj   +1 more source

Association between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation

BMC Cardiovascular Disorders, 2023
Background The objective of this study was to investigate the relationship between P2Y1 and P2Y12 genotypes and the risk of acute myocardial infarction (AMI) in the Quanzhou population and to determine associations between P2Y1 and P2Y12 genotypes and ...
Chunyan Su, Zhishan Zhang, Jintu Chen, Mengcha Tian, Conglian Wu, Tao Zhang   +5 more
doaj   +1 more source

Clinical Outcomes of Drug‐Eluting Stents and Drug‐Coated Balloons in Tortuous Small Coronary Lesions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In small, tortuous coronary lesions, the long‐term comparative performance of drug‐coated balloon (DCB) angioplasty versus drug‐eluting stent (DES) treatment remains uncertain, despite both strategies being widely used in contemporary percutaneous coronary intervention (PCI) practice. Aims This study aimed to compare 3‐year clinical
Shunichiro Ishio, Takashi Nagasaka, Ryota Taniuchi, Shiro Amanai, Yohei Ishibashi, Noriaki Takama, Hideki Ishii   +6 more
wiley   +1 more source

Primary Percutaneous Coronary Intervention Guided by High‐Definition Intravascular Ultrasound (The SPECTRUM Study)

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Limited data are available on the use of intravascular ultrasound (IVUS) in patients presenting with ST‐segment elevation myocardial infarction (STEMI). Aims This study aimed to assess the impact of IVUS‐guided primary percutaneous coronary intervention (PCI).
Frederik T. W. Groenland, Annemieke C. Ziedses des Plantes, Tara Neleman, Jurgen M. R. Ligthart, Karen T. Witberg, Rutger‐Jan Nuis, Jeroen M. Wilschut, Roberto Diletti, Wijnand K. den Dekker, Isabella Kardys, Paul Cummins, Karim D. Mahmoud, Nicolas M. Van Mieghem, Joost Daemen   +13 more
wiley   +1 more source

Temporal Trends and Prognosis in Rotational Atherectomy: A Comparison of Contemporary and Traditional Eras

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Rotational atherectomy (RA) has undergone considerable technical modernization in recent years. This study evaluated whether RA performed in the contemporary era was associated with superior cardiovascular outcomes compared with the traditional era. Aims To compare the clinical characteristics and cardiovascular outcomes of patients
Ravi Vazirani, Gonzalo García‐Martí, Andrés Provencio‐Regidor, Irene Serrano‐García, Adrián Jerónimo‐Baza, Alejandro Travieso, Gabriela Tirado‐Conte, Fernando Macaya‐Ten, Hernán Mejía‐Rentería, Pablo Salinas, Luis Nombela‐Franco, Pilar Jiménez‐Quevedo, Nieves Gonzalo, Javier Escaned, Antonio Fernández‐Ortiz, Iván J. Núñez‐Gil   +15 more
wiley   +1 more source