Results 71 to 80 of about 4,528,027 (196)
The p38 Mitogen-Activated Protein Kinase Is Involved in Associative Learning in Rabbits [PDF]
The Journal of Neuroscience, 2001 This study examined the role of the mitogen-activated protein kinase (MAPK) family during acquisition of the rabbit's classically conditioned eye-blink response. Eye-blink conditioning produced a significant, bilateral activation of both extracellular signal-regulated protein kinases (ERKs) and p38 MAPK in the anterior cerebellar vermis. There was also
X, Zhen +4 more
openaire +2 more sources
Bridelia ferruginea Produces Anti-neuroinflammatory Activity through Inhibition of Nuclear Factor-kappa B and p38 MAPK Signalling [PDF]
, 2012 Bridelia ferruginea is commonly used in traditional African medicine (TAM) for treating various inflammatory conditions. Extracts from the plant have been shown to exhibit anti-inflammatory property in a number of in vivo models.
Aderogba, Mutallib A. +7 more
core +1 more source
DUSP1 is a novel target for enhancing pancreatic cancer cell sensitivity to gemcitabine. [PDF]
PLoS ONE, 2014 Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with a poor prognosis that is characterized by excessive mitogenic pathway activation and marked chemoresistance to a broad spectrum of chemotherapeutic drugs.
Fang Liu +3 more
doaj +1 more source
p38 Mitogen-Activated Protein Kinase Regulates Vasoconstriction in Spontaneously Hypertensive Rats
Journal of Pharmacological Sciences, 2004 We investigated whether p42/p44 mitogen-activated protein kinase (MAPK) and/or p38 MAPK participates in the regulation of vascular smooth muscle contraction by endothelin-1 (ET-1) in Wistar-Kyoto rat (WKY) and spontaneously hypertensive rat (SHR).
Seongchun Kwon +5 more
doaj +1 more source
, 2011 Our findings demonstrate an integral role of the p38 mitogen-activated protein kinase pathway in interleukin 6-mediated cardiac contractile dysfunction and inotrope insensitivity.
Cheryl A. Hemingway +21 more
core +2 more sources
Poultry Science, 2020 Defensins are antimicrobial peptides composed of 3 conserved disulfide bridges, a β-sheet, and both hydrophobic and cationic amino acids. In this study, we aimed to demonstrate the immunomodulation role of avian β-defensin 8 (AvBD8) in a chicken ...
Yeojin Hong +5 more
doaj +1 more source
Nature Communications, 2016 The processes regulating the ageing of stem cells are not clearly defined. Here, the authors report that in haematopoietic stem cells (HSC) thioredoxin-interacting protein, known to regulate the cell cycle, binds to p38 mitogen-activated protein kinase ...
Haiyoung Jung +14 more
doaj +1 more source
Effects of β2-agonists and exercise on β2-adrenergic receptor signaling in skeletal muscles
Journal of Physical Fitness and Sports Medicine, 2012 In this review, we discuss the anabolic and metabolic responses of skeletal muscles to β2-agonists and exercise. β2-agonists increase muscle mass, particularly in fast-twitch muscles.
Shogo Sato +5 more
doaj +1 more source
Frontiers in Microbiology, 2019 The impact of gut microbiota and its metabolites on fat metabolism have been widely reported in human and animals. However, the critical mediators and the signal transductions are not well demonstrated.
Jian-Mei Zhang +11 more
doaj +1 more source
Crosstalk and signalling switches in mitogen-activated protein kinase cascades
Frontiers in Physiology, 2012 Mitogen-activated protein kinase (MAPK) cascades control cell fate decisions, such as proliferation, differentiation and apoptosis by integrating and processing intra- and extracellular cues.
Dirk eFey +3 more
doaj +1 more source