Effects of P38 MAPK Pathway Inhibition on the Metabolism of Periodontal Ligament Fibroblasts During Inflammation. [PDF]
Qian C +8 more
europepmc +1 more source
Calcineurin; p38 mitogen-activated protein kinase (p38 MAPK; MAPK14) [PDF]
openaire +1 more source
Mitogen-activated protein kinase 14 (MAPK14; p38) [PDF]
openaire +1 more source
What's new? Colorectal cancer (CRC) is increasingly complicated by drug‐resistant tumors that limit the effectiveness of anticancer therapies. Because resistance mechanisms vary among patients and can evolve over time, personalized treatment strategies are needed.
Keren Zohar +16 more
wiley +1 more source
Acupuncture inhibits astrocytic hyperactivationthe p38 mitogen-activated protein kinase/mitogen- and stress-activated protein kinase 1 signaling pathway in cerebral ischemia-reperfusion injury. [PDF]
Zifeng Z +6 more
europepmc +1 more source
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le +8 more
wiley +1 more source
Intersection of inflammation and viral replication: the central role of MAPK signaling in viral respiratory infections. [PDF]
Tripp RA, Jones LP, Martin DE.
europepmc +1 more source
The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis
Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan +17 more
wiley +1 more source
CMGC Kinases in Viral Infection and Human Disease. [PDF]
Amusan OT, Guo H.
europepmc +1 more source
Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
wiley +1 more source

