Results 271 to 280 of about 183,974 (371)

Activation of p38 Mitogen-Activated Protein Kinases by Endothelin and Noradrenaline in Small Arteries, Regulation by Calcium Influx and Tyrosine Kinases, and Their Role in Contraction

Arteriosclerosis, Thrombosis and Vascular Biology, 2001
J. Ohanian, Pamela Cunliffe, Enrico Ceppi, Angela C. Alder, Egidius Heerkens, V. Ohanian   +5 more
semanticscholar   +1 more source

Manipulation of the Unfolded Protein Response by Intracellular Bacterial Pathogens: Mechanisms of ER Hijacking and Therapeutic Implications

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai, Dongjie Sun, Yanxiao Zhao, Mengtao Zhang, Yifan Wu, Jiabo Ding   +5 more
wiley   +1 more source

Targeting the MAPK Pathway in Cancer. [PDF]

Int J Mol Sci
Kadasah SF.
europepmc   +1 more source

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

Microbiology and Molecular Reviews, 2011
Marie Cargnello, Philippe P Roux
semanticscholar   +1 more source

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Dissecting stress-activated protein kinase (SAPK)-signaling pathways using multiplex gene knockout HeLa cells. [PDF]

J Biol Chem
Ito C, Yamamoto M, Yokota N, Nakamura N, Shiomi M, Kizu M, Ichinose M, Fujii S, Fujii T, Fukunaga R.   +9 more
europepmc   +1 more source

P38 mitogen-activated protein kinase inhibition attenuates mechanical stress induced lung injury via up-regulating AQP5 expression in rats [PDF]

, 2019
Yang Liu, Yuelan Wang, Xiu-mei Song, Ling Dong, Wei Wang, Hong-chao Wu   +5 more
openalex   +1 more source

Frog-Derived Peptide RL-RF10 Facilitates Gingival Repair and Regeneration Through the Integrin αvβ3/p38/Snail1 Axis. [PDF]

Int Dent J
Cheng T, Zhou J, Yang H, Zhao A, Chen Y, Xianqi R, Li J, Li L, Yang X, Li Z.   +9 more
europepmc   +1 more source

In Vivo Role of p38 Mitogen-Activated Protein Kinase in Mediating the Anti-inflammatory Effects of CpG Oligodeoxynucleotide in Murine Asthma [PDF]

, 2002
Barun K. Choudhury, James S. Wild, Rafeul Alam, Dennis M. Klinman, István Boldogh, Nilesh Dharajiya, William J. Mileski, Sanjiv Sur   +7 more
openalex   +1 more source

Role of p38 mitogen-activated protein kinases in preconditioning: a detrimental factor or a protective kinase?

Circulation Research, 2000
P. Ping, E. Murphy
semanticscholar   +1 more source