Results 21 to 30 of about 17,780 (207)
New findings in cleavage sites variability across groups, subtypes and recombinants of human immunodeficiency virus type 1. [PDF]
PLoS ONE, 2014 BACKGROUND: Polymorphisms at cleavage sites (CS) can influence Gag and Pol proteins processing by the viral protease (PR), restore viral fitness and influence the virological outcome of specific antiretroviral drugs.
Esther Torrecilla +2 more
doaj +1 more source
Innovative Methods for Prenatal Cannabis Exposure: Vapor Inhalation Chamber and Metabolite Quantification in Prairie Voles and Rats. [PDF]
Dev PsychobiolABSTRACT The increasing prevalence of cannabis use, including among pregnant women, highlights the critical need for a deeper understanding of prenatal cannabis exposure. This study aimed to develop a standardized cross‐species inhalation exposure protocol to administer the principal psychoactive component of cannabis, Δ9‐tetrahydrocannabinol (THC), to
Rogers S +10 more
europepmc +2 more sources
Retrovirology, 2008 Background HIV-1 reverse transcriptase (RT) is a heterodimer composed of p66 and p51 subunits and is responsible for reverse transcription of the viral RNA genome into DNA.
Warrilow David +7 more
doaj +1 more source
Veterinary Research, 2011 Neorickettsia risticii is the Gram-negative, obligate, and intracellular bacterial pathogen responsible for Potomac horse fever (PHF): an important acute systemic disease of horses. N.
Gibson Kathryn E +3 more
doaj +1 more source
HIV-1 PR P51 Mutant Complex Formation with Inhibitors [PDF]
, 2012 Human Immunodeficiency Virus (HIV) has become a global pandemic with at least 25 million deaths and no cure. One of the most important targets to inhibit this virus is HIV-1 protease (PR), which is required to cleave the viral proteins needed for ...
Greene, Shaquita T, Zhang, Ying
core +1 more source
The coronavirus and center-peripheral relations in the economies of the European Union
International Journal of Management and Economics, 2022 From the perspective of the diversity of capitalism and that of economic sociology, the article deals with the issue of center-peripheral relations as one of the key dimensions of economic diversification that determines the development opportunities of ...
Jasiecki Krzysztof
doaj +1 more source
What kinds of countries have better innovation performance?–A country-level fsQCA and NCA study
Journal of Innovation & Knowledge, 2022 Innovation is critical to boosting economic growth and combating social problems. Based on national innovation systems, this study investigates how combinations of multiple factors (i.e., R&D investment, human capital, social freedom, democracy ...
Haien Ding
doaj +1 more source
Agriculture, 2020 Three pineapple (Ananas comosus L.) cultivation soils of the south-east Mexico were analyzed in relation to the amendment effect of two agro-industrial wastes: sugar mill filter cake (SC) and paper mill sludge (CR) jointly added by weight.
Ricardo Acevedo-Gómez +6 more
doaj +1 more source
Pesquisa Agropecuária Tropical, 2022 The knowledge on cultivars is essential for parental choosing on breeding programs. This research aimed to study the genetic divergence of Coffea arabica L.
Cyntia Stephânia dos Santos +7 more
doaj +1 more source
Interaction of primer tRNALys3 with the p51 subunit of human immunodeficiency virus type 1 reverse transcriptase: a possible role in enzyme activation [PDF]
, 1995 In the interaction between HIV-1 RT and tRNALys3 each subunit of the heterodimer interacts with tRNA showing a different affinity: Kd (p66) = 23 nM, Kd (p51) = 140 nM.
Litvak, Simon +15 more
core +1 more source