Results 41 to 50 of about 3,933 (119)
ABSTRACT The E7 oncoprotein of human papillomavirus (HPV) plays a crucial role in viral pathogenesis and replication. Although it is generally highly conserved across HPV genotypes, naturally occurring E7 variants can display functional differences that may affect viral persistence, oncogenic potential, and host cellular responses.
Zsolt Barnabás Éles +8 more
wiley +1 more source
Probiotics Cancer Interaction, Prevention, and Therapy
ABSTRACT Cancer is a significant global health concern and ranks as the second most common cause of death on a worldwide scale. A combination of hereditary and lifestyle variables, such as diet, smoking, alcohol consumption, physical exercise, and the gut microbiota, impacts cancer development. Dysbiosis, an imbalance in gut microorganisms, can promote
Mostafa Saebi +7 more
wiley +1 more source
Beyond Human Papillomavirus (HPV): Detection of EBV and Polyomaviruses in Cervical and Anal Samples
ABSTRACT Colorectal and cervical cancers represent an important public health problem worldwide, particularly in Brazil. Colorectal cancer is one of the most frequently diagnosed malignancies worldwide and the most common cancer in both men and woman in Brazil.
Ana Carolina Silva Guimarães +11 more
wiley +1 more source
What If Trojan Horse Nanoparticles Could Change the Game for HPV Gene‐Targeted Therapies?
ABSTRACT Human papillomavirus (HPV) is a common sexually transmitted infection linked to various cancers, particularly cervical cancer, primarily driven by high‐risk strains like HPV16 and HPV18. While vaccines are effective in preventing new infections, they do not address existing cases, highlighting the need for innovative therapies.
Trairong Chokwassanasakulkit +4 more
wiley +1 more source
Molecular events leading to HPV-induced high grade neoplasia
Cervical cancer is initiated by high-risk types of the human papillomavirus (hrHPV) and develops via precursor stages, called cervical intraepithelial neoplasia (CIN).
Saskia M. Wilting +1 more
doaj +1 more source
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah +4 more
wiley +1 more source
Papel das Proteínas Precoces do Papilomavírus Humano na Carcinogênese
Introdução: O Papilomavírus Humano (HPV) e um agente epiteliotrópico que apresenta mais de 100 genótipos. Destes, alguns são considerados de alto risco devido ao potencial para induzir o surgimento de lesões malignas, como o carcinoma cervical, cujo ...
Marcos Antonio Pereira de Lima +2 more
doaj +1 more source
ABSTRACT Background Human papilloma virus (HPV) is a DNA virus capable of infecting mucous membranes. In most cases, the infection is cleared by the immune system, but a prolonged exposure to HPV can progress to cancer. 40%–60% of head and neck squamous cell carcinomas (HNSCC) are linked to HPV, which is considered a risk factor especially among young ...
Michela Bulfoni +12 more
wiley +1 more source
Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro +2 more
wiley +1 more source
Key Molecular Events in Cervical Cancer Development
Cervical cancer is the fourth most common cancer among women. Infection by high-risk human papillomavirus (HPV) is the main aetiology for the development of cervical cancer. Infection by high-risk human papillomavirus (HPV) and the integration of the HPV
Shandra Devi Balasubramaniam +3 more
doaj +1 more source

