Results 221 to 230 of about 101,614 (324)

Loss of p62 Binding Allows TIF-IA Accumulation in Senescence, Which Promotes Phenotypic Changes to Nucleoli and the Senescence Associated Secretory Phenotype. [PDF]

open access: yesAging Cell
Thoms HC   +17 more
europepmc   +1 more source

Traumatic brain injury and autophagy: a pilot study about the immunohistochemical expression of LC3B, Beclin 1, p62, and LAMP2A in human autoptic samples [PDF]

open access: gold
Tommaso Livieri   +8 more
openalex   +1 more source

Tui Na Acupressure Modulates Treg Immunosuppression via FoxP3/mTORC1 Signalling in ALS Mice

open access: yesImmunology, Volume 177, Issue 3, Page 481-500, March 2026.
The proposed mechanism by which Tui Na acupressure improves motor and cognitive dysfunction in ALS mice by activating the FoxP3/mTORC1 pathway. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease driven by neuroinflammation, where regulatory T cell (Treg) dysfunction exacerbates immune imbalance.
Jie Han   +7 more
wiley   +1 more source

Comprehensive pan-cancer analysis of p62 reveals its contribution to shaping tumor microenvironment and anti-tumor immunity. [PDF]

open access: yesDiscov Oncol
Nayeri Z   +6 more
europepmc   +1 more source

Consumer Perspectives on PICU Safety and Quality

open access: yesNursing in Critical Care, Volume 31, Issue 2, March 2026.
ABSTRACT This study aimed to examine consumer perceptions and priorities for safety and quality in paediatric intensive care units (PICUs) to inform safety measurement and quality improvement efforts. We conducted a cross‐sectional, co‐designed survey distributed to PICU parents/caregivers across Australia and New Zealand.
Karina R. Charles   +10 more
wiley   +1 more source

Low-dose Simvastatin protects pancreatic cancer cells by promoting mitochondrial autophagy through TFEB. [PDF]

open access: yesCell Oncol (Dordr)
Wang Z   +16 more
europepmc   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu   +10 more
wiley   +1 more source

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