Results 31 to 40 of about 10,177 (244)
Phenotype changes of oral epithelial stem cells after in vitro culture [PDF]
Brazilian Oral Research, 2020 The aim of our study was to isolate populations of keratinocyte stem cells based on the expression of cell surface markers and to investigate whether the culture could affect their phenotype.
Felipe Perozzo DALTOE +4 more
doaj +1 more source
Science Advances, 2022 Inappropriate expansion of antibody-secreting cells (ASCs) is typical of systemic lupus erythematosus (SLE), but the regulatory signaling of pathogenic ASCs is unclear.
Wei-Yun Shen +11 more
semanticscholar +1 more source
p75NTR signal transduction suppressed by BFAR and p75NTR interactions [PDF]
Science China Life Sciences, 2012 p75NTR is a low-affinity nerve growth factor receptor, which promotes cell proliferation as a positive modulator of high-affinity receptor TrkA, as well as binds with cell ligands to induce apoptosis and mediate death signals. To analyze the regulatory mechanisms of p75NTR, the present study utilized a new membrane yeast two-hybrid system to screen a ...
HuiLi Shi, HongMei Li, KeKe Huo
openaire +3 more sources
The FASEB Journal, 2022 P75 pan‐neurotrophin receptor (p75NTR) is an important receptor for the role of neurotrophins in survival and death of neurons during development and after nerve injury. Our previous research found that the precursor of brain‐derived neurotrophic factor (
Chun-Rui Yang +13 more
semanticscholar +1 more source
Expression of NGF/proNGF and Their Receptors TrkA, p75NTR and Sortilin in Melanoma
International Journal of Molecular Sciences, 2022 There is increasing evidence that nerve growth factor (NGF) and its receptors, the neurotrophic receptor tyrosine kinase 1 (NTRK1/TrkA), the common neurotrophin receptor (NGFR/p75NTR) and the membrane receptor sortilin, participate in cancer growth.
Mark Marsland +7 more
semanticscholar +1 more source
The Effect of Interaction NGF/p75NTR in Sperm Cells: A Rabbit Model
Cells, 2022 Background: Nerve Growth Factor (NGF) plays an important role in the reproductive system through its receptor’s interaction (p75NTR). This paper aims to analyze the impact of NGF p75NTR in epididymal and ejaculated rabbit semen during in vitro sperm ...
C. Castellini +9 more
semanticscholar +1 more source
Neurotherapeutics, 2021 Huntington’s disease (HD) is caused by an expansion of the CAG repeat in the huntingtin gene leading to preferential neurodegeneration of the striatum.
Danielle A. Simmons +10 more
semanticscholar +1 more source
Aging, 2021 We aimed to explore the mechanism by which long non-coding RNA (lncRNA) OIP5-AS1 affects proNGF (precursor nerve growth factor)-induced pancreatic cancer metastasis by targeting the miR-186-5p/NGFR axis.
Ang Li +5 more
semanticscholar +1 more source
Functional interaction between p75NTR and TrkA: the endocytic trafficking of p75NTR is driven by TrkA and regulates TrkA-mediated signalling [PDF]
Biochemical Journal, 2004 The topology and trafficking of receptors play a key role in their signalling capability. Indeed, receptor function is related to the microenvironment inside the cell, where specific signalling molecules are compartmentalized. The response to NGF (nerve growth factor) is strongly dependent on the trafficking of its receptor, TrkA.
Lucio Nitsch +6 more
openaire +7 more sources
Frontiers in Cellular Neuroscience, 2019 Activation of the p75 neurotrophin receptor (p75NTR), by the proneurotrophin brain-derived neurotrophic factor (proBDNF), triggers loss of synapses and promotes neuronal death.
Andrew Speidell +5 more
doaj +1 more source