Results 11 to 20 of about 9,698 (210)

Peripheral Nerve Regeneration Is Independent From Schwann Cell p75NTR Expression [PDF]

Frontiers in Cellular Neuroscience, 2019
Schwann cell reprogramming and differentiation are crucial prerequisites for neuronal regeneration and re-myelination to occur following injury to peripheral nerves. The neurotrophin receptor p75NTR has been identified as a positive modulator for Schwann
Nádia P. Gonçalves, Nádia P. Gonçalves, Simin Mohseni, Marwa El Soury, Maj Ulrichsen, Mette Richner, Junhua Xiao, Rhiannon J. Wood, Olav M. Andersen, Elizabeth J. Coulson, Stefania Raimondo, Simon S. Murray, Christian B. Vægter, Christian B. Vægter   +13 more
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p75NTR Is Positively Promiscuous [PDF]

Neuron, 2004
Although identified almost 20 years ago, the precise physiological role of the p75 neurotrophin receptor (p75NTR) has remained elusive. Recent studies have revealed that p75NTR is a component of three distinct receptor platforms that bind different ...
Barker, Philip A
openaire   +3 more sources

Functional interaction between p75NTR and TrkA: the endocytic trafficking of p75NTR is driven by TrkA and regulates TrkA-mediated signalling [PDF]

Biochemical Journal, 2004
The topology and trafficking of receptors play a key role in their signalling capability. Indeed, receptor function is related to the microenvironment inside the cell, where specific signalling molecules are compartmentalized. The response to NGF (nerve growth factor) is strongly dependent on the trafficking of its receptor, TrkA.
Perrone L., PALADINO, SIMONA, Mazzone M., NITSCH, LUCIO, Gulisano M., ZURZOLO, CHIARA   +5 more
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p75NTR regulates postnatal skeletal development via NGF-responsive JNK signaling

Bone Reports
p75NTR has emerged as a key regulator of skeletal development and bone homeostasis. To define its role, we characterized skeletal phenotypes in global and mesenchyme-specific p75NTR knockout mouse models.
Chiho Kadota-Watanabe, Jinsook Suh, Zhenqing Liu, Eric Yin, Kate Lindsey, Isabelle Lao-Ngo, Byron Zhao, Jonathan H. Wu, In Won Chang, Reuben H. Kim, Ophir D. Klein, Christine Hong   +11 more
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Regulation and function of P75NTR

, 2012
The p75 neurotrophin receptor (p75NTR) has been known to play multiple roles in cell survival and apoptosis (Friedman, 2000; Maggirwar et al., 1998; Rabizadeh et al., 1993), axonal growth (Bentley and Lee, 2000), and cell differentiation (Hosomi et al., 2003).
Choi, Soyoung, 1976-
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Analysis of p75NTR-dependent apoptotic pathways and of p75NTR gene products

, 2003
This item was digitized as part of a project to share McGill's intellectual legacy with the public. If you are the copyright holder or a relative of the copyright holder who is deceased, you may request withdrawal by emailing escholarship.library@mcgill.ca.
Paul, Christine E.
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Reduced anxiety-like behavior and altered hippocampal morphology in female p75NTR exon IV-/- mice. [PDF]

Frontiers in Behavioral Neuroscience, 2016
The presence of the neurotrophin receptor p75NTR in adult basal forebrain cholinergic neurons, precursor cells in the subventricular cell layer and the subgranular cell layer of the hippocampus has been linked to alterations in learning as well as ...
Zoe ePuschban, Anupam eSah, Isabella eGrutsch, Nicolas eSingewald, Georg eDechant   +4 more
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Schwann Cell Apoptosis and p75NTR siRNA [PDF]

Iranian Journal of Allergy, Asthma and Immunology, 2011
The p75 pan-neurotrophin receptor (p75NTR) plays a pivotal role in linking the immune system with the nervous system. p75NTR is required for the development of several characteristic features of allergic asthma.
Masoumeh Firouzi, Farzaneh Sabouni, Abdolkhaleg Deezagi, Zahra Hassannejad Pirbasti, Fatemeh Poorrajab, Vafa Rahimi-Movaghar   +5 more
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AraC interacts with p75NTR transmembrane domain to induce cell death of mature neurons

Cell Death and Disease, 2023
Cytosine arabinoside (AraC) is one of the main therapeutic treatments for several types of cancer, including acute myeloid leukaemia. However, after a high-dose AraC chemotherapy regime, patients develop severe neurotoxicity and cell death in the central
Vanessa Lopes-Rodrigues, Pia Boxy, Eunice Sim, Dong Ik Park, Michael Habeck, Josep Carbonell, Annika Andersson, Diana Fernández-Suárez, Poul Nissen, Anders Nykjær, Lilian Kisiswa   +10 more
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Detection of p75NTR Trimers: Implications for Receptor Stoichiometry and Activation [PDF]

Journal of Neuroscience, 2015
The p75 neurotrophin receptor (p75(NTR)) is a multifunctional receptor that participates in many critical processes in the nervous system, ranging from apoptosis to synaptic plasticity and morphological events. It is a member of the tumor necrosis factor receptor (TNFR) superfamily, whose members undergo trimeric oligomerization. Interestingly, p75(NTR)
Anastasia Gonzalez, Agustin, Barker, Phillip A., Chao, Moses V., Hempstead, Barbara L.   +3 more
openaire   +5 more sources