The RelA hydrolase domain acts as a molecular switch for (p)ppGpp synthesis. [PDF]
Sinha AK, Sinha AK, Winther KS.
europepmc +1 more source
A dual program for CRP-mediated regulation in bacterial alarmone (p)ppGpp. [PDF]
Zhao L +6 more
europepmc +1 more source
Bacterial alarmone (p)ppGpp mediates the pathogenicity of <i>Clavibacter michiganensis</i> via a dual mechanism that affects both enzyme production and the Tat secretion system. [PDF]
Xu X +7 more
europepmc +1 more source
Many birds with one stone: targeting the (p)ppGpp signaling pathway of bacteria to improve antimicrobial therapy. [PDF]
Pulschen AA +5 more
europepmc +1 more source
The Emerging Role of (p)ppGpp in DNA Repair and Associated Bacterial Survival against Fluoroquinolones. [PDF]
Sivapragasam S.
europepmc +1 more source
The regulatory effects of (p)ppGpp and indole on cAMP synthesis in Escherichia coli cells. [PDF]
Kashevarova NM, Khaova EA, Tkachenko AG.
europepmc +1 more source
Genetics of conditional extended mycelial cell viability of Streptomyces minutiscleroticus in deep starvation phase implicates the involvement of (p)ppGpp, clpX, and a histidine kinase sasA. [PDF]
Chatupale V, Pohnerkar J.
europepmc +1 more source
Two P or Not Two P: Understanding Regulation by the Bacterial Second Messengers (p)ppGpp
Under stressful growth conditions and nutrient starvation, bacteria adapt by synthesizing signaling molecules that profoundly reprogram cellular physiology. At the onset of this process, called the stringent response, members of the RelA/SpoT homolog (RSH) protein superfamily are activated by specific stress stimuli to produce several ...
Gert Bange +2 more
exaly +5 more sources

