Results 131 to 140 of about 41,121 (277)

Extensions and corrections to known HLA alleles identified in PacBio results.

, 2015
Extensions and corrections to known HLA alleles identified in PacBio results.
Katy Latham (745780), Swati Ranade (745772), Patrick Marks (745777), Chen-Shan Chin (30463), Will P. Bultitude (745775), J. Alejandro Madrigal (745779), Neema P. Mayor (745770), Brett Bowman (745776), Kevin Eng (745773), Steven G. E. Marsh (5644), Alasdair J. M. McWhinnie (745771), William Midwinter (745774), James Robinson (5641), Henny Braund (745778)   +13 more
core   +1 more source

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu, Esra Isik, Basak Durmus Ozen, Mehmet Mert Topaloglu, Nihal Karadas, Kaan Kavakli, Melike Sezgin Evim, Tolga Aslan, Erşen Kavak, Adalet Meral Gunes, Funda Tayfun Kupesiz, Alphan Kupesiz, Fahri Sahin, Tahir Atik   +13 more
wiley   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Genome assembly of Elcysma westwoodi provides insights into host‐plant cyanogenic glucoside detoxification and chemical defence gene evolution

Insect Molecular Biology, EarlyView.
A chromosome‐level genome of Elcysma westwoodi was assembled. The genome encodes 272 detoxification‐related genes. A single‐copy bCAS was retained for cyanide detoxification. CYP405A and CYP332A were recruited into cyanogenic defence evolution. UGT33A retained a conserved GT‐B fold and catalytic domains.
Minyoung Choi, Murtaza Khan, Juil Kim
wiley   +1 more source

Supplementary Materials, PacBio metagenomics data binning

, 2018
Supplementary ...
openaire   +1 more source

High‐quality genome of elite peanut cultivar ZH05 reveals subgenome asymmetry, pan‐genome diversity, and breeding insights

Journal of Integrative Plant Biology, EarlyView.
A high‐quality reference genome for the elite peanut cultivar Zhonghua No. 5 revealed differing evolutionary paths between the two peanut subgenomes. SubA has higher overall gene expression and more open chromatin, whereas SubB has stronger structural organization, higher DNA methylation, and greater adaptive diversity associated with peanut evolution ...
Taihua Yang, Nian Liu, Li Huang, Jianbin Guo, Xiaomeng Xue, Mingjun Wang, Xiaohan Zhang, Chengtao Quan, Enyou Feng, Jiazhuang Tan, Zhenzhen Zhang, Yu You, Youlin Xia, Dongxin Huai, Yuning Chen, Liyin Yan, Kede Liu, Huifang Jiang, Yong Lei, Boshou Liao   +19 more
wiley   +1 more source

Processing of Pacbio Iso-seq sequences v1

, 2017
This protocol is to further process the sequences generated from ICE and Quiver.
openaire   +1 more source

Anomalies observed in the PacBio SMRT consensus sequences as compared to the expected allele.

, 2015
Anomalies observed in the PacBio SMRT consensus sequences as compared to the expected allele.
Katy Latham (745780), Swati Ranade (745772), Patrick Marks (745777), Chen-Shan Chin (30463), Will P. Bultitude (745775), J. Alejandro Madrigal (745779), Neema P. Mayor (745770), Brett Bowman (745776), Kevin Eng (745773), Steven G. E. Marsh (5644), Alasdair J. M. McWhinnie (745771), William Midwinter (745774), James Robinson (5641), Henny Braund (745778)   +13 more
core   +1 more source

Climate‐driven niche filtering limits post‐dispersal establishment and genomic introgression in a riverine shrub

Journal of Integrative Plant Biology, EarlyView.
Integrated biogeographic analysis and macroecological insights reveal that habitat differences drive genetic differentiation Debregeasia orientalis C. J. Chen, a dominant riparian shrub distributed across multiple biodiversity hotspots, and different lineages vary greatly in adaptability to future climate.
Zeng‐Yuan Wu, Mark A. Chapman, Richard I. Milne, Jie Liu, Ya‐Huang Luo, Peng‐Zhen Fan, Guang‐Fu Zhu, Jason T. Weir, Richard T. Corlett, Xiao‐Gang Fu, Toby P. N. Tsang, Marc W. Cadotte, De‐Zhu Li   +12 more
wiley   +1 more source

Telomere‐to‐telomere CHM13 reference reveals missing truth variants and improves deep learning‐based variant calling in long‐read sequencing data [PDF]

Quant Biol
Abstract Although long‐read sequencing enables comprehensive genomic analysis, its potential is hindered by its reliance on the incomplete GRCh38 reference genome. GRCh38’s unresolved bases, structural errors, and haplotype mosaics introduce reference biases, leading to missed variants and false‐positive calls.
Zheng Z, He M, Yu X, Chen L, Li J, Zhang J, Luo R.   +6 more
europepmc   +2 more sources