Results 121 to 130 of about 41,121 (277)
Improving PacBio Long Read Accuracy by Short Read Alignment
PLoS ONE, 2012 The recent development of third generation sequencing (TGS) generates much longer reads than second generation sequencing (SGS) and thus provides a chance to solve problems that are difficult to study through SGS alone. However, higher raw read error rates are an intrinsic drawback in most TGS technologies.
Kin Fai Au +3 more
openaire +4 more sources
Cladistics, EarlyView.Abstract A long‐standing challenge in phylogenomics has been the resolution of relationships originated from ancient radiations. In these cases, phenomena such as incomplete lineage sorting can increase the support for conflicting resolutions. Most of the diversity in the Class Bivalvia originated during an Ordovician radiation; indeed, several deep ...
Alessandro Formaggioni +7 more
wiley +1 more source
PacBio long-read sequencing v1
The barcoded library is also sequenced via PacBio long-read sequencing to associate variants with particular barcodes. This allows for the generation of a variant-barcode map along the length of the protein of interest, to which variant scores can be mapped.
Nicholas A. Popp +4 more
openaire +1 more source
PacBio assemblies from Khost et al 2017
, 2017 Five PacBio assemblies of D. melanogaster ISO1 strain used in Khost et al 2017 (doi: https://doi.org/10.1101/054155) This paper focuses on assembly and structure of satellite DNA loci in D. mel.
Larracuente, Amanda +2 more
core +1 more source
Genetic testing in paediatric neurological disorders
Developmental Medicine &Child Neurology, EarlyView.In this study 390 paediatric patients with neurological disorders underwent genetic testing via exome sequencing, commercial panel, in‐house epilepsy, and movement disorder gene panels. Exome sequencing provides the highest diagnostic yield, and severe developmental delay and hypotonia predicted pathogenic variants in the exome sequencing cohort ...
Wafa Bani Uraba +15 more
wiley +1 more source
PacBio assemblies of Cryptococcus neoformans var grubii genomes
, 2018 PacBio assemblies of three Cryptococcus neoformans var grubii genomes. PI on the project, Jeremy Day, Oxford University Clinical Research Unit (OUCRU)
Philip Ashton (402326)
core +1 more source
Post‐Hoc Long‐Read Sequencing Links Leukemic Mutation Status to Single‐Cell Transcriptomes
European Journal of Haematology, EarlyView.ABSTRACT Single‐cell RNA‐sequencing‐based characterization of cells that belong to the neoplastic clone is a major challenge in hematologic neoplasms, where malignant and normal cells coexist. Confident molecular profiling requires simultaneous analysis of gene expression and genetic mutations in individual cells, an ability that is not supported by ...
Sofia Papavasileiou +8 more
wiley +1 more source
PacBio Iso-Seq transcriptome sequencing of Diorhabda carinulata tissues
, 2022 PacBio Iso-Seq transcriptome sequencing of Diorhabda carinulata (northern tamarisk beetle) head, thorax, and abdomen of three adult females was conducted by the USDA-ARS Ag100Pest ...
United States Department of Agriculture (17854922)
core
International Journal of Cosmetic Science, EarlyView.A 28‐day clinical study in 41 individuals with oily dandruff showed that a piroctone olamine shampoo improved clinical symptoms while selectively reshaping the scalp bacterial and fungal microbiome toward a less dysbiotic profile. Abstract Objective To evaluate the clinical efficacy of a piroctone olamine–containing shampoo in individuals with oily ...
Spyridon Markos +4 more
wiley +1 more source
Enterococcus faecium ATCC_8459 PacBio/Illumina Sequencing Project
, 2013 Enterococcus faecium ATCC_8459 PacBio/Illumina Sequencing, Hybrid Assembly and Comparative Analysis ...
Broad Institute (17855168)
core