Results 111 to 120 of about 48,352 (276)

P472: Highly scalable pharmacogenomic panel testing with hybrid capture and long-read sequencing*

Genetics in Medicine Open, 2023
Nina Gonzaludo, Sarah Kingan, John Harting, Primo Baybayan, Siyuan Zhang, Tina Han, Leonardo Arbiza, Yao Yang, Nathan Hammond, Stuart Scott   +9 more
doaj   +1 more source

PacBio long-read sequencing v1

The barcoded library is also sequenced via PacBio long-read sequencing to associate variants with particular barcodes. This allows for the generation of a variant-barcode map along the length of the protein of interest, to which variant scores can be mapped.
Nicholas A. Popp, Melinda K. Wheelock, Raining Wang, Rachel L. Powell, Douglas M. Fowler   +4 more
openaire   +1 more source

Improved Draft Genome Sequence of Microbacterium sp. Strain LKL04, a Bacterial Endophyte Associated with Switchgrass Plants. [PDF]

, 2019
We report here the genome assembly and analysis of Microbacterium strain sp. LKL04, a Gram-positive bacterial endophyte isolated from switchgrass plants (Panicum virgatum) grown on a reclaimed coal-mining site.
Bokros, Norbert, DeBolt, Seth, Kyrpides, Nikos C, Sahib, Mohammad Radhi, Shapiro, Nicole, Woyke, Tanja, Xia, Ye, Yang, Piao   +7 more
core   +1 more source

From Pine Cones to Read Clouds: Rescaffolding the Megagenome of Sugar Pine (Pinus lambertiana). [PDF]

, 2017
We investigate the utility and scalability of new read cloud technologies to improve the draft genome assemblies of the colossal, and largely repetitive, genomes of conifers.
Crepeau, Marc W, Langley, Charles H, Stevens, Kristian A   +2 more
core   +2 more sources

Snake Gut Microbiota as a Source of Anti‐Inflammatory Probiotics: Isolation and Functional Characterization of Two Novel Strains

Integrative Zoology, EarlyView.
This study assessed the probiotic potential of intestinal microbiomes from five snake species using metagenomics and in vitro isolation, identifying two promising strains (Lactobacillus johnsonii DA0116 and Limosilactobacillus reuteri DA0218) through comprehensive screening.
Xuena Kang, Lan Hu, Jiarong Song, Zhenjie Zhang, Yi Li, Qingqing Zhang, Cuiling Luo, Yu Pang, Peng Guo, Bisong Yue, Ping Li, Zhenxin Fan   +11 more
wiley   +1 more source

Leveraging multiple sequencing technologies to generate a haplotype specific assembly of sugarcane R570. [W1018] [PDF]

, 2020
While sugarcane is one of the world's most important economic grasses for its sugar production and biofuel potential, tools and resources to understand its genetics are lacking.
Aitken, Karen S., D'Hont, Angélique, Garsmeur, Olivier, Grimwood, Jane, Healey, Adam, Henry, Robert, Jenkins, Jerry, Lovell, John, Schmutz, Jeremy   +8 more
core  

Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure [PDF]

, 2017
The natural environment serves as a reservoir of opportunistic pathogens. A well-established method for studying the epidemiology of such opportunists is multilocus sequence typing, which in many cases has defined strains predisposed to causing infection.
Peeters, Charlotte, Cooper, Vaughn S, Hatcher, Philip J, Verheyde, Bart, Carlier, Aurélien, Vandamme, Peter   +5 more
core   +3 more sources

PacBio long read sequencing v1

, 2018

openaire   +1 more source

217 closed Salmonella reference genomes using PacBio sequencing

BMC Genomic Data
Abstract Objectives Whole Genome Sequencing (WGS) is widely used in food safety for the detection, investigation, and control of foodborne bacterial pathogens. However, the WGS data in most public databases, such as the National Center for Biotechnology Information (NCBI), primarily consist of Illumina short reads ...
Yan Luo, Jae Hee Jang, Maria Balkey, Maria Hoffmann   +3 more
openaire   +3 more sources

Rapid construction of insect–plant interaction networks via multiplexed long‐fragment DNA metabarcoding and NGS

Methods in Ecology and Evolution, EarlyView.
Abstract Molecular identification of insect food webs can accurately reveal complex trophic interactions and serve as a foundation for understanding ecosystem functioning and advancing biodiversity conservation. This process typically involves DNA library construction, high‐throughput sequencing and subsequent steps, including data assembly, annotation,
Xiao‐man Zhang, Yu‐xuan Zheng, Shao‐jun Zhang, Cai‐qing Yang, Xin‐chun Li, Qian Jin, Jing Li, Liu‐sheng Chen, Ai‐bing Zhang, Jing‐ze Liu   +9 more
wiley   +1 more source