Results 51 to 60 of about 47,490 (285)

Highly Resolved Community Sewage Metagenomics Unveiling Landscape and Transmission Patterns of Antibiotic Resistome in Hong Kong Populations

Advanced Science, EarlyView.
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding, Mengying Wang, Xiaoqing Xu, Dou Wang, Xi Chen, Shuxian Li, Xiawan Zheng, You Che, Yu Deng, Tommy T. Y. Lam, Liguan Li, Tong Zhang   +11 more
wiley   +1 more source

The complete mitochondrial genome of Patagonian moray cod, Muraenolepis orangiensis Vaillant, 1888 (Gadiformes, Muraenolepididae)

Mitochondrial DNA. Part B. Resources, 2020
The full-length mitochondrial genome of Muraenolepis orangiensis (Vaillant, 1888) was studied using PacBio platform and it is first report in a Muraenolepididae family.
Eunkyung Choi, Seong Hee Park, Seung Jae Lee, Euna Jo, Jinmu Kim, Jeong-Hoon Kim, Jin-Hyoung Kim, Jong Seok Lim, Hyun Park   +8 more
doaj   +1 more source

Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing [PDF]

Human Mutation, 2017
Cytochrome P450 2D6 (CYP2D6) is among the most important genes involved in drug metabolism. Specific variants are associated with changes in the enzyme's amount and activity. Multiple technologies exist to determine these variants, like the AmpliChip CYP450 test, Taqman qPCR, or Second-Generation Sequencing, however, sequence homology between ...
Buermans, H.P.J., Vossen, R.H.A.M., Anvar, S.Y., Allard, W.G., Guchelaar, H.J., White, S.J., Dunnen, J.T. den, Swen, J.J., Straaten, T. van der   +8 more
openaire   +3 more sources

Improving nanopore read accuracy with the R2C2 method enables the sequencing of highly multiplexed full-length single-cell cDNA. [PDF]

, 2018
High-throughput short-read sequencing has revolutionized how transcriptomes are quantified and annotated. However, while Illumina short-read sequencers can be used to analyze entire transcriptomes down to the level of individual splicing events with ...
Byrne, Ashley, Cole, Charles, Green, Richard E, Palmer, Theron, Schmitz, Robert J, Volden, Roger, Vollmers, Christopher   +6 more
core   +1 more source

Comprehensive profiling of rhizome-associated alternative splicing and alternative polyadenylation in moso bamboo (Phyllostachys edulis). [PDF]

, 2017
Moso bamboo (Phyllostachys edulis) represents one of the fastest-spreading plants in the world, due in part to its well-developed rhizome system. However, the post-transcriptional mechanism for the development of the rhizome system in bamboo has not been
Cai, Dawei, Gao, Yubang, Gu, Lianfeng, Lin, Chentao, Ma, Liuyin, Wang, Huiyuan, Wang, Taotao, Wang, Yongsheng, Zhang, Hangxiao   +8 more
core   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Complex structural variant visualization with SVTopo

BMC Genomics
Background Structural variants are genomic variants that impact at least 50 nucleotides. Structural variants can play major roles in diversity and human health.
Jonathan R. Belyeu, William J. Rowell, Juniper A. Lake, James Matthew Holt, Zev Kronenberg, Christopher T. Saunders, Michael A. Eberle   +6 more
doaj   +1 more source

The complete mitochondrial genome of Macrourus whitsoni (Gadiformes, Macrouridae)

Mitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome of Macrourus witsoni was determined in this study by the Long-read Technology, such as PacBio Sequel System. The Long-read Technology, which can sequence continuously the whole vertebrate mitochondrial genome, allows ...
Seung Jae Lee, Tae-Eul Im, Euna Jo, Eunkyung Choi, Young Min Chi, Jin-Hyoung Kim, Jeong-Hoon Kim, Hyun Park   +7 more
doaj   +1 more source

LongQC: A Quality Control Tool for Third Generation Sequencing Long Read Data

G3: Genes, Genomes, Genetics, 2020
We propose LongQC as an easy and automated quality control tool for genomic datasets generated by third generation sequencing (TGS) technologies such as Oxford Nanopore technologies (ONT) and SMRT sequencing from Pacific Bioscience (PacBio).
Yoshinori Fukasawa, Luca Ermini, Hai Wang, Karen Carty, Min-Sin Cheung   +4 more
doaj   +1 more source

Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution [PDF]

, 2018
Although Plasmodium vivax is responsible for the majority of malaria infections outside Africa, little is known about its evolution and pathway to humans. Its closest genetic relative, P.
Arnathau, Céline, Boundenga, Larson, Durand, Patrick, Franzon, Blaise, Gilabert, Aude, Makanga, Boris, Moukodoum, Nancy D., Ngoubangoye, Barthélémy, Okouga, Alain-Prince, Ollomo, Benjamin, Otto, Thomas D., Paupy, Christophe, Prugnolle, Franck, Renaud, François, Rougeron, Virginie, Rutledge, Gavin G.   +15 more
core   +5 more sources