Results 51 to 60 of about 48,352 (276)

The complete chloroplast genome of the Chinese banyan tree Ficus microcarpa

Mitochondrial DNA. Part B. Resources, 2022
Banyan tree or Ficus microcarpa is a large perennial plant with extraordinary aerial roots from the Moraceae family. In this study, the complete chloroplast genome sequence of F. microcarpa was assembled using PacBio data.
Enwen Lin, Zhenyang Liao, Xiuming Xu, Xingtan Zhang, Jingping Fang   +4 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

Advanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan, Xueyang Li, Cong He, Pan Zheng, Yaoyu Zou, Qi Zhu, Xin Li, Jie Liang, Junmin Yang, Li Zhang, Yuman Ye, Jianhua Wan, Huajing Ke, Jianping Liu, Nonghua Lu, Nianshuang Li, Yin Zhu   +16 more
wiley   +1 more source

The complete mitochondrial genome of Patagonian moray cod, Muraenolepis orangiensis Vaillant, 1888 (Gadiformes, Muraenolepididae)

Mitochondrial DNA. Part B. Resources, 2020
The full-length mitochondrial genome of Muraenolepis orangiensis (Vaillant, 1888) was studied using PacBio platform and it is first report in a Muraenolepididae family.
Eunkyung Choi, Seong Hee Park, Seung Jae Lee, Euna Jo, Jinmu Kim, Jeong-Hoon Kim, Jin-Hyoung Kim, Jong Seok Lim, Hyun Park   +8 more
doaj   +1 more source

Improving nanopore read accuracy with the R2C2 method enables the sequencing of highly multiplexed full-length single-cell cDNA. [PDF]

, 2018
High-throughput short-read sequencing has revolutionized how transcriptomes are quantified and annotated. However, while Illumina short-read sequencers can be used to analyze entire transcriptomes down to the level of individual splicing events with ...
Byrne, Ashley, Cole, Charles, Green, Richard E, Palmer, Theron, Schmitz, Robert J, Volden, Roger, Vollmers, Christopher   +6 more
core   +1 more source

A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion [PDF]

, 2017
The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise the Roseolovirus genus of the human Betaherpesvirinae subfamily. Infections with these viruses have been implicated in many
Beatrice Plougastel-Douglas, Daved H. Fremont, David Wang, Elvin J. Lauron, Eugene Park, Guoyan Zhao, Ian B. Harvey, Jennifer Poursine-Laurent, Swapneel J. Patel, Vinay R. Penna, Wandy L. Beatty, Wayne M. Yokoyama   +11 more
core   +2 more sources

Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing [PDF]

Human Mutation, 2017
Cytochrome P450 2D6 (CYP2D6) is among the most important genes involved in drug metabolism. Specific variants are associated with changes in the enzyme's amount and activity. Multiple technologies exist to determine these variants, like the AmpliChip CYP450 test, Taqman qPCR, or Second-Generation Sequencing, however, sequence homology between ...
Buermans, H.P.J., Vossen, R.H.A.M., Anvar, S.Y., Allard, W.G., Guchelaar, H.J., White, S.J., Dunnen, J.T. den, Swen, J.J., Straaten, T. van der   +8 more
openaire   +3 more sources

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

Advanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei, Yu Zhou, Haitao Sun, Hang Yuan, Xinyu Pei, Jessica D. Hess, Yao Yan, Zunsong Hu, Mian Zhou, Zhaohui Gu, Li Zheng, Xiwei Wu, Binghui Shen   +12 more
wiley   +1 more source

Complex structural variant visualization with SVTopo

BMC Genomics
Background Structural variants are genomic variants that impact at least 50 nucleotides. Structural variants can play major roles in diversity and human health.
Jonathan R. Belyeu, William J. Rowell, Juniper A. Lake, James Matthew Holt, Zev Kronenberg, Christopher T. Saunders, Michael A. Eberle   +6 more
doaj   +1 more source

The complete mitochondrial genome of Macrourus whitsoni (Gadiformes, Macrouridae)

Mitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome of Macrourus witsoni was determined in this study by the Long-read Technology, such as PacBio Sequel System. The Long-read Technology, which can sequence continuously the whole vertebrate mitochondrial genome, allows ...
Seung Jae Lee, Tae-Eul Im, Euna Jo, Eunkyung Choi, Young Min Chi, Jin-Hyoung Kim, Jeong-Hoon Kim, Hyun Park   +7 more
doaj   +1 more source

LongQC: A Quality Control Tool for Third Generation Sequencing Long Read Data

G3: Genes, Genomes, Genetics, 2020
We propose LongQC as an easy and automated quality control tool for genomic datasets generated by third generation sequencing (TGS) technologies such as Oxford Nanopore technologies (ONT) and SMRT sequencing from Pacific Bioscience (PacBio).
Yoshinori Fukasawa, Luca Ermini, Hai Wang, Karen Carty, Min-Sin Cheung   +4 more
doaj   +1 more source