Results 101 to 110 of about 6,359 (194)

Beyond PAD Inhibition: Emerging Avenues and Natural Products for Targeting Citrullination in Immune Diseases. [PDF]

Biomedicines
Chen Q, Ma Y, Liu Y, Wang X, Huang G, Yang Y, Ko JK, Chen H.   +7 more
europepmc   +1 more source

PAD4 takes charge

Citrullination comprises the enzymatic modification of peptidylarginine to peptidylcitrulline by peptidyl arginine deiminase (PAD) enzymes. The role of citrullination in innate immunity has particularly sparked scientific interest after the finding that histone citrullination is involved in formation of neutrophil extracellular traps (NETs).
openaire   +2 more sources

Roles of peptidylarginine deiminase (PAD) and protein citrullination in viral infections. [PDF]

Front Microbiol
Wang K, Ma T, Ouyang M, Fei X, Yang L, Guo G.   +5 more
europepmc   +1 more source

IL-17A Promotes NETs Formation via the PKCζ-ERK-ROS-PAD4 Pathway in a Mouse Model of Ischemic Stroke. [PDF]

CNS Neurosci Ther
Liu C, Chen Q, Chen W, Han X, Qiao X, Guo J, Su W, Dai Q.   +7 more
europepmc   +1 more source

Targeting Peptidylarginine Deiminases in Neurons and Astrocytes in Central Nervous System Injury-Effects of Pan-PAD Inhibitor Cl-Amidine in an Oxygen-Glucose Deprivation Model of Ischaemia (OGD/R) and LPS Stimulation In Vitro. [PDF]

Int J Mol Sci
Ahmed D, Getting SJ, Ashioti M, Lange S.
europepmc   +1 more source

Neutrophil extracellular traps in the animal model of adenine-induced chronic kidney disease. [PDF]

PLoS One
Gaál Kovalčíková A, Forraiová G, Korotushak N, Borbélyová V, Vavrincová-Yaghi D, Vavrinec P, Podracká Ľ, Celec P.   +7 more
europepmc   +1 more source

PAD4 and von Willebrand Factor Link Inflammation and Thrombosis [PDF]

Circulation Research, 2019
Craig N, Morrell, Zachary T, Hilt, Daphne N, Pariser, Preeti, Maurya   +3 more
openaire   +2 more sources

Neutrophil Extracellular Trap Formation-Derived Peptidylarginine Deiminases in the Citrullination of Oral Bacteria to Promote Inflammation in Rheumatoid Arthritis. [PDF]

J Rheumatol
Acharya S, Brewer RC, Gomez AM, Younis S, Pandit M, Jahanbani S, Sharpe O, Love ZZ, Howard MC, Orange DE, Robinson WH.   +10 more
europepmc   +1 more source

Assembly of helper NLR resistosome clusters upon activation of a coiled-coil NLR. [PDF]

Nature
Ge D, Ortiz-Morea FA, Xie Y, Yeo IC, Shen Q, Zhou Y, Liu G, Kong L, Shan L, He P.   +9 more
europepmc   +1 more source

Anti-PAD4 antibodies link autoimmunity to PAD4 with CTL-associated rheumatoid arthritis

Annals of the Rheumatic Diseases
Kusuma Ananth, Katharine B Moosic, Eduardo Gomez-Banuelos, Hong Wang, Isabel Trejo-Zambrano, Ramona Johnson, Jessica Marie Kirschmann, Tess Deddens, Omar Elghawy, Bryna Shemo, William H Robinson, Donald Kimpel, Clifton O Bingham, David J Feith, Brendan Antiochos, Felipe Andrade, Thomas P Loughran, Erika Darrah   +17 more
openaire   +1 more source