Results 11 to 20 of about 2,661 (192)
Biological Activities of Paeonol in Cardiovascular Diseases: A Review [PDF]
Molecules, 2021 Paeonol is a naturally existing bioactive compound found in the root bark of Paeonia suffruticosa and it is traditionally used in Chinese medicine for the prevention and management of cardiovascular diseases.
Shalini Vellasamy +5 more
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Anti-tumor effects of paeonol in melanoma by up-regulating miR-143 and suppressing its target WNT5B
STEMedicine, 2023 Previous studies have shown the potent anti-tumor effect of paeonol, a natural compound extracted from traditional Chinese herb medicine. However, the therapeutic effect and underlying mechanisms of paeonol in melanoma are largely unknown.
Meishan Piao, Guangdong Feng
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ASN Neuro, 2021 Intracerebral haemorrhage (ICH) is a devastating subtype of stroke with high morbidity and mortality. It has been reported that paeonol (PAN) inhibits the progression of ICH. However, the mechanism by which paeonol mediates the progression of ICH remains
Zheng-Long Jin +6 more
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Antioxidants, 2022 Paeonol is a naturally occurring phenolic agent that attenuates neurotoxicity in neurodegenerative diseases. We aimed to investigate the antioxidant and protective effects of paeonol and determine its transport mechanism in wild-type (WT; NSC-34/hSOD1WT)
Sana Latif +5 more
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A review on therapeutical potential of paeonol in atherosclerosis
Frontiers in Pharmacology, 2022 The morbidity and mortality of atherosclerotic cardiovascular disease (ASCVD) is increasing year by year. Cortex Moutan is a traditional Chinese medicinal herb that has been widely used for thousands of years to treat a wide variety of diseases in ...
Wei Yu +4 more
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Paeonol-Loaded Ethosomes as Transdermal Delivery Carriers: Design, Preparation and Evaluation
Molecules, 2018 Paeonol exhibits a wide range of pharmacological activities, such as anti-inflammatory, antidiabetic as well as pain-relieving activities. However, its intrinsic properties, such as low water solubility, poor stability and low oral bioavailability ...
Hongdan Ma +5 more
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Molecules, 2023 Endometriosis is a common gynecological illness in women of reproductive age that significantly decreases life quality and fertility. Paeonol has been shown to play an important part in endometriosis treatments.
Jing Liu +7 more
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Antifungal activity of paeonol against Botrytis cinerea by disrupting the cell membrane and the application on cherry tomato preservation [PDF]
Frontiers in MicrobiologyBotrytis cinerea may cause gray mold in fruits and vegetables. Paeonol, an active component of traditional Chinese medicine, could suppress various microbial growth. However, reports on its effect on B. cinerea have not yet been documented. In this paper,
Yang Jiao +6 more
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Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice. [PDF]
PLoS ONE, 2016 Acetaminophen (APAP) overdose is the most frequent cause of drug-induced acute liver failure. The purpose of this study was to investigate whether paeonol protected against APAP-induced hepatotoxicity.
Yi Ding +6 more
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Pharmacokinetics, Tissue Distribution and Excretion of Paeonol and Its Major Metabolites in Rats Provide a Further Insight Into Paeonol Effectiveness [PDF]
Frontiers in Pharmacology, 2020 Paeonol is a major bioactive ingredient in Moutan Cortex (the root barks of Paeonia suffruticosa Andrews) and exhibited a wide range of bioactivities such as anti-inflammation, anti-oxidation, hypoglycemic effect, analgesic, and others.
Xintong Hu +14 more
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