Results 31 to 40 of about 2,661 (192)
MoleculesMoutan Cortex (MC) is a traditional Chinese medicine that contains abundant medicinal components, such as paeonol, paeoniflorin, etc. Paeonol is the main active component of MC.
Ling Meng +8 more
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Pharmacokinetics of Purified Paeonol and Paeonol in Moutan Cortex Decoction and Rhubarbmoutan Decoction [PDF]
Pharmaceutica Analytica Acta, 2011 180 KM male mice of 22~28g body weight were divided into three groups randomly and purified paeonol, Moutan Cortex decoction and Rhubarbmoutan decoction were orally administered at equivalent doses of 10 mg·kg -1 paeonol. A sensitive HPLC method was established and evaluated for determining the concentrations of paeonol in mice ...
Wu Jing, Zhang Rui, Yuan Gui-yan
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Frontiers in Cardiovascular Medicine, 2021 With improvement in living standards and average life expectancy, atherosclerotic cardiovascular disease incidences and mortality have been increasing annually.
Min Wu +8 more
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Paeonol enhances TRAIL-induced apoptosis of human lung cancer cells by upregulating death receptors-4 and 5 via ROS-JNK/ERK-CHOP signaling [PDF]
, 2022 Purpose: To study the anti-proliferative potential of paeonol against lung cancer cells, and investigate its mechanism of action. Methods: Cell viability after paeonol treatment was determined with 3-(4,5-dimethylthiazol-2yl)2,5- diphenyltetrazolium ...
Chen, Xiaoyan +5 more
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Paeonol attenuates inflammation by confining HMGB1 to the nucleus [PDF]
Journal of Cellular and Molecular Medicine, 2021 AbstractInflammation is a biological process that exists in a large number of diseases. If the magnitude or duration of inflammation becomes uncontrolled, inflammation may cause pathological damage to the host. HMGB1 and NF‐κB have been shown to play pivotal roles in inflammation‐related diseases.
Jifei Miao +9 more
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Aquaculture Reports, 2022 This experiment was conducted to determine the effect of dietary paeonol levels on growth performance, serum biochemical parameters, antioxidant enzyme activities and transcriptional expression of antioxidant- and immune-related genes in Genetic ...
Yaxue Li +7 more
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Frontiers in Pharmacology, 2020 Background: Targeting inflammatory microenvironment is a promising anti-tumor strategy. Paeonol is a phenolic compound with effective anti-inflammatory and anti-tumor properties.
Lei Zhang +16 more
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Modulating Effect of Paeonol on Piglets With Ulcerative Colitis
Frontiers in Nutrition, 2022 Piglet enteritis is a major problem that needs to be solved urgently in modern pig production. Paeonol (Pae) has been used as a novel treatment option due to its good medicinal value. This study purported to elucidate the regulatory mechanism of Pae on dextran sodium sulfate (DSS)-induced ulcerative colitis (UC) in weaned piglets.
Shanshan Wang +8 more
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Frontiers in Immunology, 2022 Developing quorum-sensing (QS) based anti-infection drugs is one of the most powerful strategies to combat multidrug-resistant bacteria. Paeonol has been proven to attenuate the QS-controlled virulence factors of P.
Huaqiao Tang +9 more
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Antidepressant-like Effect of Paeonol [PDF]
Pharmaceutical Biology, 2006 AbstractThe current study investigated the putative antidepressant-like effect of paeonol, a phenolic component from the root bark of Paeonia suffruticosa. Andr. (Ranunculaceae), in mice or rats using the tail suspension test (TST) and forced swimming test (FST), two widely accepted pharmacological models for detecting antidepressant activity in modern
Weili Zhu +3 more
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